Insecticidal Constituents and Activity of Alkaloids from Cynanchum mongolicum
AbstractBased on MS and NMR data and bioassay-guided tracing, three insecticidal alkaloids I, II and III from Cynanchum mongolicum were identified to be antofine N-oxide, antofine and tylophorine. Alkaloid I was more toxic than alkaloids II and III, but they were less active against Spodoptera litura than total alkaloids. The contact toxicity from these alkaloids against the aphid Lipaphis erysimi was significant, as the 24 h-LC50 values of alkaloids I, II, III and total alkaloids were 292.48, 367.21, 487.791 and 163.52 mg/L, respectively. The development disruption of S. litura larvae was tested, the pupation and emergence rates of S. litura decreased and the acute mortality of S. litura increased significantly by day 3 after being injected in their body cavity with 10–40 mg/L of total alkaloid. The ecdysone titer of treated S. litura larvae and prepupae declined with increasing alkaloid concentration. The alkaloids of Cynanchum mongolicum are potential insect growth inhibitors. View Full-Text
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Ge, Y.; Liu, P.; Yang, R.; Zhang, L.; Chen, H.; Camara, I.; Liu, Y.; Shi, W. Insecticidal Constituents and Activity of Alkaloids from Cynanchum mongolicum. Molecules 2015, 20, 17483-17492.
Ge Y, Liu P, Yang R, Zhang L, Chen H, Camara I, Liu Y, Shi W. Insecticidal Constituents and Activity of Alkaloids from Cynanchum mongolicum. Molecules. 2015; 20(9):17483-17492.Chicago/Turabian Style
Ge, Yang; Liu, Pingping; Yang, Rui; Zhang, Liu; Chen, Hongxing; Camara, Ibrahima; Liu, Yiqing; Shi, Wangpeng. 2015. "Insecticidal Constituents and Activity of Alkaloids from Cynanchum mongolicum." Molecules 20, no. 9: 17483-17492.