Absorption-Enhancing Effects of Bile Salts
AbstractBile salts are ionic amphiphilic compounds with a steroid skeleton. Among the most important physiological properties of bile salts are lipid transport by solubilization and transport of some drugs through hydrophobic barriers. Bile salts have been extensively studied to enhance transepithelial permeability for different marker molecules and drugs. They readily agglomerate at concentrations above their critical micelle concentration (CMC). The mechanism of absorption enhancement by bile salts appears to be complex. The aim of the present article was to review bile salt structure and their application as absorption enhancers and the probable mechanism for increasing permeation based on previous studies. View Full-Text
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Moghimipour, E.; Ameri, A.; Handali, S. Absorption-Enhancing Effects of Bile Salts. Molecules 2015, 20, 14451-14473.
Moghimipour E, Ameri A, Handali S. Absorption-Enhancing Effects of Bile Salts. Molecules. 2015; 20(8):14451-14473.Chicago/Turabian Style
Moghimipour, Eskandar; Ameri, Abdulghani; Handali, Somayeh. 2015. "Absorption-Enhancing Effects of Bile Salts." Molecules 20, no. 8: 14451-14473.