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Molecules 2015, 20(3), 4967-4997; doi:10.3390/molecules20034967

Synthesis of C-Arylnucleoside Analogues

1
Sorbonne Universités, Université de Technologie de Compiègne, Ecole Supérieure de Chimie Organique et Minérale, Transformations Intégrées de la Matière Renouvelable, Centre de Recherche Royallieu, CS 60319, Compiègne cedex F-60203, France
2
Department of Chemistry, University of Hull, Hull HU6 7RX, UK
*
Author to whom correspondence should be addressed.
Academic Editor: Derek J. McPhee
Received: 24 January 2015 / Accepted: 10 March 2015 / Published: 18 March 2015
(This article belongs to the Special Issue 20th Anniversary of Molecules—Recent Advances in Organic Chemistry)

Abstract

Modified nucleoside analogues are of great biological importance as antiviral and antitumoral agents. There is special interest in the preparation of C-aryl nucleosides with an aromatic ring in different positions of the glycone for their biological activity. Different chemical synthesis strategies for these targets are described in this review. View Full-Text
Keywords: C-arylnucleoside; nucleoside; carbohydrate; total synthesis; asymmetric catalysis C-arylnucleoside; nucleoside; carbohydrate; total synthesis; asymmetric catalysis
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Len, C.; Enderlin, G. Synthesis of C-Arylnucleoside Analogues. Molecules 2015, 20, 4967-4997.

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