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Molecules 2015, 20(1), 127-134; doi:10.3390/molecules20010127

Xanthones from the Roots of Moutabea guianensis Aubl.

1
Instituto de Ciências Exatas e Naturais, Universidade Federal do Pará-UFPA, Rua Augusto Corrêa, S/N, 66075-900 Belém-PA, Brazil
2
Programa de Pós-Graduação em Biotecnologia, Instituto de Ciências Biológicas, Universidade Federal do Pará-UFPA, Rua Augusto Corrêa, S/N, 66075-900 Belém-PA, Brazil
*
Author to whom correspondence should be addressed.
Academic Editor: Derek J. McPhee
Received: 16 September 2014 / Accepted: 28 November 2014 / Published: 23 December 2014
(This article belongs to the Section Natural Products)
View Full-Text   |   Download PDF [515 KB, uploaded 23 December 2014]   |  

Abstract

The phytochemical investigation of Moutabea guianensis roots led to the isolation of five polyoxygenated xanthones, including two new ones named moutabeone B (1,8-dihydroxy-4,5,6,7-tetramethoxyxanthone) and moutabeone C (1-hydroxy-4,5,6,7,8-pentamethoxyxanthone), along with the three known xanthones, 1,8-dihydroxy-4,6-dimethoxyxanthone, 1,8-dihydroxy-4,5,6-trimethoxyxanthone and augustin A (1,8-dihydroxy-4,6,7-trimethoxyxanthone). Structural characterization of all compounds was established on the basis of spectroscopic methods, mainly 1D and 2D nuclear magnetic resonance (NMR) and comparison with literature data. The antioxidant activity of compounds was tested through a thin layer chromatography (TLC) bioautography assay using 1,1-diphenyl-2-picryl-hydrazyl radical (DPPH·) as detection reagent. All tested compounds were more active (DL < 0.13–0.03 µg) than Trolox (DL < 0.15 µg), used as reference standard. View Full-Text
Keywords: Moutabea guianensis; Polygalaceae; xanthones; antioxidant activity Moutabea guianensis; Polygalaceae; xanthones; antioxidant activity
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Filho, H.S.R.; Pacheco, L.C.; Andrade, E.S.; Correa, M.J.C.; Araújo, R.N.M.; Guilhon, G.M.S.P.; Silva, J.K.R.; Santos, L.S. Xanthones from the Roots of Moutabea guianensis Aubl.. Molecules 2015, 20, 127-134.

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