Molecules 1997, 2(9), 129-134; doi:10.3390/20900129
Article

Improved Method for the Synthesis of New 1,5-Benzothiazepine Derivatives as Analogues of Anticancer Drugs

Anoop K. Sharma, Gajendra Singh, Ashok K. Yadav and L. Prakash*
Department of Chemistry, University of Rajasthan, Jaipur - 302 004 India
* Author to whom correspondence should be addressed.
Received: 10 April 1997 / Accepted: 1 August 1997 / Published: 5 September 1997
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Abstract: (±)cis-2-(4-Methoxyphenyl)-3-hydroxy/methoxy-2,3-dihydro-1,5-benzothiazepin-4[5H/5-chloroacetyl/5-(4'-methylpiperazino-1')acetyl]-ones have been synthesized by the condensation of 2-aminobenzene thiols with methyl(±)trans-3-(4-methoxyphenyl)glycidate in xylene. The synthesized compounds have been characterized by elemental analyses and spectral data and screened for their antimicrobial activity.
Keywords: 1; 5-Benzothiazepin derivatives; anticancer drugs

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MDPI and ACS Style

Sharma, A.K.; Singh, G.; Yadav, A.K.; Prakash, L. Improved Method for the Synthesis of New 1,5-Benzothiazepine Derivatives as Analogues of Anticancer Drugs. Molecules 1997, 2, 129-134.

AMA Style

Sharma AK, Singh G, Yadav AK, Prakash L. Improved Method for the Synthesis of New 1,5-Benzothiazepine Derivatives as Analogues of Anticancer Drugs. Molecules. 1997; 2(9):129-134.

Chicago/Turabian Style

Sharma, Anoop K.; Singh, Gajendra; Yadav, Ashok K.; Prakash, L. 1997. "Improved Method for the Synthesis of New 1,5-Benzothiazepine Derivatives as Analogues of Anticancer Drugs." Molecules 2, no. 9: 129-134.

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