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Molecules 2014, 19(9), 13422-13431; doi:10.3390/molecules190913422

A New Cycloartane-Type Triterpenoid Saponin Xanthine Oxidase Inhibitor from Homonoia riparia Lour

1
Kunming General Hospital of Chengdu Military Region, Kunming 650032, Yunnan, China
2
The First Affiliated Hospital of Kunming Medical University, Kunming 650031, Yunnan, China
*
Author to whom correspondence should be addressed.
Received: 30 June 2014 / Revised: 6 August 2014 / Accepted: 7 August 2014 / Published: 29 August 2014
(This article belongs to the Section Natural Products)
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Abstract

A new cycloartane-type triterpenoid saponin named riparsaponin (1) was isolated from the stem of Homonoia riparia Lour together with six known compounds. The structure of riparsaponin was determined by using NMR and mass spectroscopy and X-ray crystallography techniques. Additionally, riparsaponin has a significant inhibitory effect on xanthine oxidase in vitro, and the IC50 was 11.16 nmol/mL. View Full-Text
Keywords: Homonoia riparia Lour; cycloartane-type triterpenoid saponin; xanthine oxidase inhibitors Homonoia riparia Lour; cycloartane-type triterpenoid saponin; xanthine oxidase inhibitors
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This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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MDPI and ACS Style

Xu, F.; Zhao, X.; Yang, L.; Wang, X.; Zhao, J. A New Cycloartane-Type Triterpenoid Saponin Xanthine Oxidase Inhibitor from Homonoia riparia Lour. Molecules 2014, 19, 13422-13431.

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