Synthesis of Functionalized Arylaziridines as Potential Antimicrobial Agents
AbstractBy using the Suzuki-Miyaura protocol, a simple straightforward synthesis of functionalized 2-arylaziridines has been developed. By means of this synthetic strategy from readily available ortho-, meta- and para-bromophenylaziridines and aryl- or heteroarylboronic acids, new aziridines could be obtained. The cross-coupling reactions occurred without ring opening of the three membered ring. Preliminary results on the antimicrobial activity of the heterosubstituted biaryl compounds have been also included. View Full-Text
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Giovine, A.; Muraglia, M.; Florio, M.A.; Rosato, A.; Corbo, F.; Franchini, C.; Musio, B.; Degennaro, L.; Luisi, R. Synthesis of Functionalized Arylaziridines as Potential Antimicrobial Agents. Molecules 2014, 19, 11505-11519.
Giovine A, Muraglia M, Florio MA, Rosato A, Corbo F, Franchini C, Musio B, Degennaro L, Luisi R. Synthesis of Functionalized Arylaziridines as Potential Antimicrobial Agents. Molecules. 2014; 19(8):11505-11519.Chicago/Turabian Style
Giovine, Arianna; Muraglia, Marilena; Florio, Marco A.; Rosato, Antonio; Corbo, Filomena; Franchini, Carlo; Musio, Biagia; Degennaro, Leonardo; Luisi, Renzo. 2014. "Synthesis of Functionalized Arylaziridines as Potential Antimicrobial Agents." Molecules 19, no. 8: 11505-11519.