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Natural Dibenzo-α-Pyrones and Their Bioactivities
AbstractNatural dibenzo-α-pyrones are an important group of metabolites derived from fungi, mycobionts, plants and animal feces. They exhibit a variety of biological activities such as toxicity on human and animals, phytotoxicity as well as cytotoxic, antioxidant, antiallergic, antimicrobial, antinematodal, and acetylcholinesterase inhibitory properties. Dibenzo-α-pyrones are biosynthesized via the polyketide pathway in microorganisms or metabolized from plant-derived ellagitannins and ellagic acid by intestinal bacteria. At least 53 dibenzo-α-pyrones have been reported in the past few decades. This mini-review aims to briefly summarize the occurrence, biosynthesis, biotransformation, as well as their biological activities and functions. Some considerations related to synthesis, production and applications of dibenzo-α-pyrones are also discussed.
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Mao, Z.; Sun, W.; Fu, L.; Luo, H.; Lai, D.; Zhou, L. Natural Dibenzo-α-Pyrones and Their Bioactivities. Molecules 2014, 19, 5088-5108.View more citation formats
Mao Z, Sun W, Fu L, Luo H, Lai D, Zhou L. Natural Dibenzo-α-Pyrones and Their Bioactivities. Molecules. 2014; 19(4):5088-5108.Chicago/Turabian Style
Mao, Ziling; Sun, Weibo; Fu, Linyun; Luo, Haiyu; Lai, Daowan; Zhou, Ligang. 2014. "Natural Dibenzo-α-Pyrones and Their Bioactivities." Molecules 19, no. 4: 5088-5108.