Next Article in Journal
Previous Article in Journal
Molecules 2014, 19(3), 3401-3416; doi:10.3390/molecules19033401
Article

Regioselective Electrophilic Aromatic Bromination: Theoretical Analysis and Experimental Verification

1, 1,* , 2, 2,* , 3 and 3
Received: 24 February 2014; in revised form: 10 March 2014 / Accepted: 13 March 2014 / Published: 20 March 2014
View Full-Text   |   Download PDF [352 KB, updated 18 June 2014; original version uploaded 18 June 2014]
Abstract: Electrophilic aromatic bromination is the most common synthetic method used to prepare aryl bromides, which are very useful intermediates in organic synthesis. To understand the experimental results in electrophilic aromatic brominations, ab initio calculations are used here for a tentative analysis of the positional selectivity. The calculated results agree well with the corresponding experimental data, and the reliability of the resulting positional selectivity was verified by the corresponding experimental data.
Keywords: electrophilic aromatic bromination; selectivity; ab initio; natural products electrophilic aromatic bromination; selectivity; ab initio; natural products
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Export to BibTeX |
EndNote


MDPI and ACS Style

Li, H.-J.; Wu, Y.-C.; Dai, J.-H.; Song, Y.; Cheng, R.; Qiao, Y. Regioselective Electrophilic Aromatic Bromination: Theoretical Analysis and Experimental Verification. Molecules 2014, 19, 3401-3416.

AMA Style

Li H-J, Wu Y-C, Dai J-H, Song Y, Cheng R, Qiao Y. Regioselective Electrophilic Aromatic Bromination: Theoretical Analysis and Experimental Verification. Molecules. 2014; 19(3):3401-3416.

Chicago/Turabian Style

Li, Hui-Jing; Wu, Yan-Chao; Dai, Jian-Hong; Song, Yan; Cheng, Runjiao; Qiao, Yuanyuan. 2014. "Regioselective Electrophilic Aromatic Bromination: Theoretical Analysis and Experimental Verification." Molecules 19, no. 3: 3401-3416.


Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert