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Molecules 2014, 19(3), 3068-3083; doi:10.3390/molecules19033068
Article

Synthesis of Novel Highly Functionalized 4-Thiazolidinone Derivatives from 4-Phenyl-3-thiosemicarbazones

1,2
,
3
,
1
,
3
 and
3,*
1 Laboratoire de Synthèse Organique Appliquée, BP 1524, El Menaouer, Département de Chimie, Faculté des Sciences Exactes et Appliquées, Université d'Oran, Oran 31000, Algeria 2 Sciences et Techniques, Faculté des Sciences & Technologie, Université de Mascara, Mascara 29000, Algeria 3 Aix-Marseille Université, Institut de Chimie Radicalaire ICR, UMR CNRS 7273, Laboratoire de Pharmaco-Chimie Radicalaire, Faculté de Pharmacie, 27 Boulevard Jean Moulin, Marseille cedex 05 13385, France
* Author to whom correspondence should be addressed.
Received: 7 February 2014 / Revised: 27 February 2014 / Accepted: 4 March 2014 / Published: 11 March 2014
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Abstract

We present herein the synthesis in good yields of two series of highly functionalized thiazolidinone derivatives from the reactions of various 4-phenyl-3-thio-semicarbazones with ethyl 2-bromoacetate and diethyl acetylenedicarboxylate, respectively.
Keywords: 4-phenyl-3-thiosemicarbazones; thiazolidinones derivatives; ethyl 2-bromoacetate; diethyl acetylenedicarboxylate 4-phenyl-3-thiosemicarbazones; thiazolidinones derivatives; ethyl 2-bromoacetate; diethyl acetylenedicarboxylate
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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Benmohammed, A.; Khoumeri, O.; Djafri, A.; Terme, T.; Vanelle, P. Synthesis of Novel Highly Functionalized 4-Thiazolidinone Derivatives from 4-Phenyl-3-thiosemicarbazones. Molecules 2014, 19, 3068-3083.

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