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Molecules 2014, 19(3), 3004-3011; doi:10.3390/molecules19033004

Limonoids from the Fruits of Khaya ivorensis

1,2, 3, 1,2, 1, 1, 1,*  and 1,*
1 CAS Key Laboratory of Tropical Plant Resource and Sustainable Use, Xishuangbanna Tropical Botanical Garden, Chinese Academy of Sciences, Menglun, Mengla, Yunnan 666303, China 2 University of Chinese Academy of Sciences, Beijing 100049, China 3 Engineering Research Center for the Development and Application of Ethnic Medicines and TCM, School of Pharmacy, Guiyang Medical College, 9 Beijing Road, Guiyang, Guizhou 550004, China
* Authors to whom correspondence should be addressed.
Received: 22 January 2014 / Revised: 27 February 2014 / Accepted: 28 February 2014 / Published: 7 March 2014
(This article belongs to the Section Natural Products)
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Two new limonoids, namely 14,15-didehydroruageanin A (1) and 3-O-methyl- butyrylseneganolide A (2), were isolated from the fruits of Khaya ivorensis along with six known limonoids: seneganolide A (3), 1,3-dideacetylkhivorin (4), 7-deacetylkhivorin (5), 3-deacetylkhivorin (6), 1-deacetylkhivorin (7), and 3-deacetyl-7-oxokhivorin (8). All the compounds were evaluated for their cytotoxicity against five tumor cell lines.
Keywords: Khaya ivorensis; limonoids; 14,15-didehydroruageanin A; 3-O-methylbutyryl- seneganolide A; cytotoxicity Khaya ivorensis; limonoids; 14,15-didehydroruageanin A; 3-O-methylbutyryl- seneganolide A; cytotoxicity
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Ji, K.-L.; Liao, S.-G.; Zheng, X.-L.; Na, Z.; Hu, H.-B.; Zhang, P.; Xu, Y.-K. Limonoids from the Fruits of Khaya ivorensis. Molecules 2014, 19, 3004-3011.

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