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Molecules 2014, 19(3), 3004-3011; doi:10.3390/molecules19033004
Article

Limonoids from the Fruits of Khaya ivorensis

1,2, 3, 1,2, 1, 1, 1,*  and 1,*
1 CAS Key Laboratory of Tropical Plant Resource and Sustainable Use, Xishuangbanna Tropical Botanical Garden, Chinese Academy of Sciences, Menglun, Mengla, Yunnan 666303, China 2 University of Chinese Academy of Sciences, Beijing 100049, China 3 Engineering Research Center for the Development and Application of Ethnic Medicines and TCM, School of Pharmacy, Guiyang Medical College, 9 Beijing Road, Guiyang, Guizhou 550004, China
* Authors to whom correspondence should be addressed.
Received: 22 January 2014 / Revised: 27 February 2014 / Accepted: 28 February 2014 / Published: 7 March 2014
(This article belongs to the Section Natural Products)
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Abstract

Two new limonoids, namely 14,15-didehydroruageanin A (1) and 3-O-methyl- butyrylseneganolide A (2), were isolated from the fruits of Khaya ivorensis along with six known limonoids: seneganolide A (3), 1,3-dideacetylkhivorin (4), 7-deacetylkhivorin (5), 3-deacetylkhivorin (6), 1-deacetylkhivorin (7), and 3-deacetyl-7-oxokhivorin (8). All the compounds were evaluated for their cytotoxicity against five tumor cell lines.
Keywords: Khaya ivorensis; limonoids; 14,15-didehydroruageanin A; 3-O-methylbutyryl- seneganolide A; cytotoxicity Khaya ivorensis; limonoids; 14,15-didehydroruageanin A; 3-O-methylbutyryl- seneganolide A; cytotoxicity
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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Ji, K.-L.; Liao, S.-G.; Zheng, X.-L.; Na, Z.; Hu, H.-B.; Zhang, P.; Xu, Y.-K. Limonoids from the Fruits of Khaya ivorensis. Molecules 2014, 19, 3004-3011.

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