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Molecules 2014, 19(1), 819-825; doi:10.3390/molecules19010819
Article

Pestalafuranones F–J, Five New Furanone Analogues from the Endophytic Fungus Nigrospora sp. BM-2

, * , , ,  and *
Hubei Key Laboratory of Natural Products Research and Development, College of Chemistry and Life Science, China Three Gorges University, Yichang 443002, China
* Authors to whom correspondence should be addressed.
Received: 9 December 2013 / Revised: 3 January 2014 / Accepted: 3 January 2014 / Published: 10 January 2014
(This article belongs to the Section Natural Products)
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Abstract

Five new 2(5H)-furanone-type derivatives, pestalafuranones F–J (compounds 37), together with two known compounds, pestalafuranones A (1) and B (2), were isolated from the ethyl acetate extract from the fermentation broth of the endophytic fungus Nigrospora sp. BM-2 in a hypersaline medium. The structures of these metabolites were elucidated by EIMS, HREIMS and NMR spectroscopic data. Compounds 17 exhibited no cytotoxic activities against the MDA-MB-231 and Caski cancer cell lines.
Keywords: pestalafuranones F–J; endophytic fungus; Nigrospora sp.; cytotoxic activity pestalafuranones F–J; endophytic fungus; Nigrospora sp.; cytotoxic activity
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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Zhang, H.; Deng, Z.; Guo, Z.; Tu, X.; Wang, J.; Zou, K. Pestalafuranones F–J, Five New Furanone Analogues from the Endophytic Fungus Nigrospora sp. BM-2. Molecules 2014, 19, 819-825.

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