Next Article in Journal
Inhibition of Epstein-Barr Virus Lytic Cycle by an Ethyl Acetate Subfraction Separated from Polygonum cuspidatum Root and Its Major Component, Emodin
Previous Article in Journal
Construction of the 1,2-Dialkenylcyclohexane Framework via Ireland-Claisen Rearrangement and Intramolecular Barbier Reaction: Application to the Synthesis of (±)-Geijerone and a Diastereoisomeric Mixture with Its 5-Epimer
Molecules 2014, 19(1), 1250-1257; doi:10.3390/molecules19011250
Article

Two New Secondary Metabolites from Xylaria sp. cfcc 87468

1,†
, 2,†
, 1
, 2
, 2
, 1
, 1
, 1,*  and 2,*
1 Department of Pharmacy, Wuhan First Hospital, Wuhan 430022, Hubei, China 2 Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, Hubei, China These two authors contributed equally to this work.
* Authors to whom correspondence should be addressed.
Received: 5 December 2013 / Revised: 15 January 2014 / Accepted: 15 January 2014 / Published: 20 January 2014
View Full-Text   |   Download PDF [286 KB, uploaded 18 June 2014]   |   Browse Figures

Abstract

A new isocoumarin glycoside, 3R-(+)-5-O-[6'-O-acetyl]-α-D-glucopyranosyl-5-hydroxymellein (1), and a new phenylethanol glycoside, (−)-phenylethyl-8-O-α-L-rhamno-pyranoside (2), were isolated from the ethyl acetate extract of the fungus Xylaria sp. cfcc 87468, together with five known steroids, β-sitosterol (3), stigmast-4-en-3-one (4), ergosterol (5), (22E)-cholesta-4,6,8(14),22-tetraen-3-one (6), and 4α-methyl- ergosta-8(14),24(28)-dien-3β-ol (7). The structures of compounds 1 and 2 were elucidated by MS, extensive 1D and 2D NMR spectroscopy, and the circular dichroism (CD) spectroscopy.
Keywords: Xylaria; isocoumarin glycoside; phenylethanol glycoside; steroids Xylaria; isocoumarin glycoside; phenylethanol glycoside; steroids
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Share & Cite This Article

Export to BibTeX |
EndNote


MDPI and ACS Style

Wang, F.; Han, S.; Hu, S.; Xue, Y.; Wang, J.; Xu, H.; Chen, L.; Zhang, G.; Zhang, Y. Two New Secondary Metabolites from Xylaria sp. cfcc 87468. Molecules 2014, 19, 1250-1257.

View more citation formats

Supplement

Related Articles

Article Metrics

Comments

Citing Articles

[Return to top]
Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert