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Two New Secondary Metabolites from Xylaria sp. cfcc 87468
Department of Pharmacy, Wuhan First Hospital, Wuhan 430022, Hubei, China
Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, Hubei, China
These two authors contributed equally to this work.
* Authors to whom correspondence should be addressed.
Received: 5 December 2013; in revised form: 15 January 2014 / Accepted: 15 January 2014 / Published: 20 January 2014
Abstract: A new isocoumarin glycoside, 3R-(+)-5-O-[6'-O-acetyl]-α-D-glucopyranosyl-5-hydroxymellein (1), and a new phenylethanol glycoside, (−)-phenylethyl-8-O-α-L-rhamno-pyranoside (2), were isolated from the ethyl acetate extract of the fungus Xylaria sp. cfcc 87468, together with five known steroids, β-sitosterol (3), stigmast-4-en-3-one (4), ergosterol (5), (22E)-cholesta-4,6,8(14),22-tetraen-3-one (6), and 4α-methyl- ergosta-8(14),24(28)-dien-3β-ol (7). The structures of compounds 1 and 2 were elucidated by MS, extensive 1D and 2D NMR spectroscopy, and the circular dichroism (CD) spectroscopy.
Keywords: Xylaria; isocoumarin glycoside; phenylethanol glycoside; steroids
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MDPI and ACS Style
Wang, F.; Han, S.; Hu, S.; Xue, Y.; Wang, J.; Xu, H.; Chen, L.; Zhang, G.; Zhang, Y. Two New Secondary Metabolites from Xylaria sp. cfcc 87468. Molecules 2014, 19, 1250-1257.
Wang F, Han S, Hu S, Xue Y, Wang J, Xu H, Chen L, Zhang G, Zhang Y. Two New Secondary Metabolites from Xylaria sp. cfcc 87468. Molecules. 2014; 19(1):1250-1257.
Wang, Fuqian; Han, Shishi; Hu, Song; Xue, Yongbo; Wang, Jianping; Xu, Hongfeng; Chen, Lu; Zhang, Geng; Zhang, Yonghui. 2014. "Two New Secondary Metabolites from Xylaria sp. cfcc 87468." Molecules 19, no. 1: 1250-1257.