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Molecules 2013, 18(9), 10122-10131; doi:10.3390/molecules180910122

Variation of Vitamin D in Cow’s Milk and Interaction with β-Lactoglobulin

, 1,* , 2
, 3
 and 1
Received: 1 July 2013 / Revised: 14 August 2013 / Accepted: 15 August 2013 / Published: 22 August 2013
(This article belongs to the Section Metabolites)
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Abstract: Vitamin D is the collective name for a group of closely related lipids, whose main biological function is to maintain serum calcium and phosphorus concentrations within the normal range by enhancing the efficiency of the small intestine to absorb these minerals from the diet. We used a commercially available ELISA method for the determination of vitamin D in bovine milk. Individual milk samples from two different Italian Friesian herds were analysed. The enzyme immunoassay method used was confirmed as a useful tool to measure the vitamin D in the milk as it greatly reduces the time required to perform the conventional HPLC analysis. An interesting variation was found among individual animals that may be associated with management factors and specific genetic effects. A relationship was highlighted between vitamin D and the genetic polymorphism of β-lactoglobulin, the main bovine whey protein which is involved in the transport of small hydrophobic molecules such as retinol and vitamin D. The relatively high content of vitamin D in most milk samples suggests an opportunity to improve the natural content of vitamin D in milk either by acting on the herd management or selecting individuals genetically predisposed to produce milk with a higher vitamin D content.
Keywords: vitamin D; bovine milk; β-lactoglobulin vitamin D; bovine milk; β-lactoglobulin
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Bulgari, O.; Caroli, A.M.; Chessa, S.; Rizzi, R.; Gigliotti, C. Variation of Vitamin D in Cow’s Milk and Interaction with β-Lactoglobulin. Molecules 2013, 18, 10122-10131.

AMA Style

Bulgari O, Caroli AM, Chessa S, Rizzi R, Gigliotti C. Variation of Vitamin D in Cow’s Milk and Interaction with β-Lactoglobulin. Molecules. 2013; 18(9):10122-10131.

Chicago/Turabian Style

Bulgari, Omar; Caroli, Anna M.; Chessa, Stefania; Rizzi, Rita; Gigliotti, Carmen. 2013. "Variation of Vitamin D in Cow’s Milk and Interaction with β-Lactoglobulin." Molecules 18, no. 9: 10122-10131.

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