Uncarilic Acid and Secouncarilic Acid, Two New Triterpenoids from Uucaria sessilifructus
AbstractTwo new compounds, the 6-oxo oleanane-type triterpenoid uncarilic acid, and its 5,6-secotriterpenoid derivative, secouncarilic acid, were isolated from the hooks and stems of Uucaria sessilifructus together with seven known ursane-type triterpenoids. Uncarilic acid is the second 6-oxo oleanane-type triterpenoid ever reported, while secouncarilic acid is the first oleanane-type 5,6-secotriterpenoid. A plausible biosynthetic pathway from uncarilic acid to secouncarilic acid was also postulated. The inhibitory activities of all the nine compounds against LPS-induced nitric oxide production in RAW264.7 macrophages were evaluated.
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Zhang, M.-J.; Liu, B.; Liao, S.-G.; Xu, Y.-K.; Feng, D.-Q.; Ji, K.-L.; Li, Y. Uncarilic Acid and Secouncarilic Acid, Two New Triterpenoids from Uucaria sessilifructus. Molecules 2013, 18, 9727-9734.
Zhang M-J, Liu B, Liao S-G, Xu Y-K, Feng D-Q, Ji K-L, Li Y. Uncarilic Acid and Secouncarilic Acid, Two New Triterpenoids from Uucaria sessilifructus. Molecules. 2013; 18(8):9727-9734.Chicago/Turabian Style
Zhang, Mao-Juan; Liu, Bing; Liao, Shang-Gao; Xu, You-Kai; Feng, De-Qiang; Ji, Kai-Long; Li, Yan. 2013. "Uncarilic Acid and Secouncarilic Acid, Two New Triterpenoids from Uucaria sessilifructus." Molecules 18, no. 8: 9727-9734.