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Three Novel Xanthones from Garcinia paucinervis and Their Anti-TMV Activity
Yunnan Academy of Tobacco Agricultural Sciences, Yuxi 653100, China
Key Laboratory of Tobacco Chemistry of Yunnan Province, Yunnan Academy of Tobacco Science, Kunming 650106, China
Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission and Ministry of Education, Yunnan University of Nationalities, Kunming 650031, China
* Authors to whom correspondence should be addressed.
Received: 6 June 2013; in revised form: 2 August 2013 / Accepted: 5 August 2013 / Published: 13 August 2013
Abstract: Phytochemical investigations of the leaves of Garcinia paucinervis resulted in the isolation of three new xanthones 1–3 and five known analogues 4–8. Structural elucidations of 1–3 were performed by spectral methods such as 1D and 2D (HMQC, HMBC, and ROESY) NMR spectroscopy, in addition to high resolution mass spectrometry. Compounds 1–3 showed anti-TMV activities, with inhibition rates above 20%, especially for 1, which had a lower IC50 value of 21.4 µM.
Keywords: Garcinia paucinervis; xanthones; anti-tobacco mosaic virus
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Cite This Article
MDPI and ACS Style
Wu, Y.-P.; Zhao, W.; Xia, Z.-Y.; Kong, G.-H.; Lu, X.-P.; Hu, Q.-F.; Gao, X.-M. Three Novel Xanthones from Garcinia paucinervis and Their Anti-TMV Activity. Molecules 2013, 18, 9663-9669.
Wu Y-P, Zhao W, Xia Z-Y, Kong G-H, Lu X-P, Hu Q-F, Gao X-M. Three Novel Xanthones from Garcinia paucinervis and Their Anti-TMV Activity. Molecules. 2013; 18(8):9663-9669.
Wu, Yu-Ping; Zhao, Wei; Xia, Zhen-Yuan; Kong, Guang-Hui; Lu, Xiu-Ping; Hu, Qiu-Fen; Gao, Xue-Mei. 2013. "Three Novel Xanthones from Garcinia paucinervis and Their Anti-TMV Activity." Molecules 18, no. 8: 9663-9669.