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Molecules 2013, 18(8), 10081-10094; doi:10.3390/molecules180810081
Article

Evaluation of Silica-H2SO4 as an Efficient Heterogeneous Catalyst for the Synthesis of Chalcones

1
, 1,* , 1
, 2
, 3
 and 4,*
1 Ibn e Sina Block, Department of Chemistry, University of Sargodha, Sargodha 40100, Pakistan 2 HEJ Research Institute of Chemistry, International Centre for Chemical & Biological Sciences, University of Karachi, Karachi 75270, Pakistan 3 Ibn ul Haithum Block, Department of Physics, University of Sargodha, Sargodha 40100, Pakistan 4 Department of Food Science, University Putra Malaysia, UPM 43400, Serdang, Malaysia
* Authors to whom correspondence should be addressed.
Received: 19 July 2013 / Revised: 5 August 2013 / Accepted: 7 August 2013 / Published: 20 August 2013
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Abstract

We report an efficient silica-H2SO4 mediated synthesis of a variety of chalcones that afforded the targeted compounds in very good yield compared to base catalyzed solvent free conditions as well as acid or base catalyzed refluxing conditions.
Keywords: silica-H2SO4; solvent free conditions; chalcone; arylidene indanone; arylidene tetralone; Claisen-Schmidt condensation silica-H2SO4; solvent free conditions; chalcone; arylidene indanone; arylidene tetralone; Claisen-Schmidt condensation
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Sultan, A.; Raza, A.R.; Abbas, M.; Khan, K.M.; Tahir, M.N.; Saari, N. Evaluation of Silica-H2SO4 as an Efficient Heterogeneous Catalyst for the Synthesis of Chalcones. Molecules 2013, 18, 10081-10094.

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