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Molecules 2013, 18(8), 10081-10094; doi:10.3390/molecules180810081
Article

Evaluation of Silica-H2SO4 as an Efficient Heterogeneous Catalyst for the Synthesis of Chalcones

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Received: 19 July 2013 / Revised: 5 August 2013 / Accepted: 7 August 2013 / Published: 20 August 2013
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Abstract

We report an efficient silica-H2SO4 mediated synthesis of a variety of chalcones that afforded the targeted compounds in very good yield compared to base catalyzed solvent free conditions as well as acid or base catalyzed refluxing conditions.
Keywords: silica-H2SO4; solvent free conditions; chalcone; arylidene indanone; arylidene tetralone; Claisen-Schmidt condensation silica-H2SO4; solvent free conditions; chalcone; arylidene indanone; arylidene tetralone; Claisen-Schmidt condensation
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Sultan, A.; Raza, A.R.; Abbas, M.; Khan, K.M.; Tahir, M.N.; Saari, N. Evaluation of Silica-H2SO4 as an Efficient Heterogeneous Catalyst for the Synthesis of Chalcones. Molecules 2013, 18, 10081-10094.

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