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Molecules 2013, 18(8), 10081-10094; doi:10.3390/molecules180810081

Evaluation of Silica-H2SO4 as an Efficient Heterogeneous Catalyst for the Synthesis of Chalcones

1
Ibn e Sina Block, Department of Chemistry, University of Sargodha, Sargodha 40100, Pakistan
2
HEJ Research Institute of Chemistry, International Centre for Chemical & Biological Sciences, University of Karachi, Karachi 75270, Pakistan
3
Ibn ul Haithum Block, Department of Physics, University of Sargodha, Sargodha 40100, Pakistan
4
Department of Food Science, University Putra Malaysia, UPM 43400, Serdang, Malaysia
*
Authors to whom correspondence should be addressed.
Received: 19 July 2013 / Revised: 5 August 2013 / Accepted: 7 August 2013 / Published: 20 August 2013
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Abstract

We report an efficient silica-H2SO4 mediated synthesis of a variety of chalcones that afforded the targeted compounds in very good yield compared to base catalyzed solvent free conditions as well as acid or base catalyzed refluxing conditions.
Keywords: silica-H2SO4; solvent free conditions; chalcone; arylidene indanone; arylidene tetralone; Claisen-Schmidt condensation silica-H2SO4; solvent free conditions; chalcone; arylidene indanone; arylidene tetralone; Claisen-Schmidt condensation
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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MDPI and ACS Style

Sultan, A.; Raza, A.R.; Abbas, M.; Khan, K.M.; Tahir, M.N.; Saari, N. Evaluation of Silica-H2SO4 as an Efficient Heterogeneous Catalyst for the Synthesis of Chalcones. Molecules 2013, 18, 10081-10094.

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