Abstract: Tyrosinase enzyme is a monophenol monoxygenase enzyme, which plays an important role in human as a rate limiting step enzyme for different specific metabolic pathways, as well as its useful application in industry and agriculture. So this study was carried out to test the effect of newly prepared compounds containing 1,3,4-oxadiazoles with different substituted groups on tyrosinase enzyme activity, hoping to use them in the treatment of some diseases arising from tyrosinase activity disorders such as Parkinson’s disease, schizophrenia, autism, attention deficit, hyperactivity disorder, and cancer.
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El Sadek, M.M.; Hassan, S.Y.; Abdelwahab, H.E.; Yacout, G.A. Synthesis and Bioassay of a New Class of Furanyl-1,3,4-Oxadiazole Derivatives. Molecules 2013, 18, 8550-8562.
El Sadek MM, Hassan SY, Abdelwahab HE, Yacout GA. Synthesis and Bioassay of a New Class of Furanyl-1,3,4-Oxadiazole Derivatives. Molecules. 2013; 18(7):8550-8562.
El Sadek, Mohamed M.; Hassan, Seham Y.; Abdelwahab, Huda E.; Yacout, Galila A. 2013. "Synthesis and Bioassay of a New Class of Furanyl-1,3,4-Oxadiazole Derivatives." Molecules 18, no. 7: 8550-8562.