Molecules 2013, 18(6), 7239-7252; doi:10.3390/molecules18067239
Article

Enhancement of the Controlled-Release Properties of Chitosan Membranes by Crosslinking with Suberoyl Chloride

email, email, email and * email
Received: 6 May 2013; in revised form: 7 June 2013 / Accepted: 17 June 2013 / Published: 19 June 2013
(This article belongs to the Section Natural Products)
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: A novel crosslinking agent, suberoyl chloride, was used to crosslink N-phthaloyl acylated chitosan and improves the properties of chitosan membranes. Membranes with different crosslinking degrees were synthesized. The derivatives were characterized by Fourier transform infrared spectroscopy and 13C solid state nuclear magnetic resonance spectroscopy, which indicated that the crosslinking degrees ranged from 0 to 7.4%. The permeabilities of various plant nutrients, including macroelements (N, P, K), microelements (Zn2+ and Cu2+), and a plant growth regulator (naphthylacetic acid), were varied by moderate changes in crosslinking degree, indicating that the controlled-release properties can be regulated in this way. The film-forming ability of native chitosan was maintained, whilst mechanical properties, hydrophobicity and controlled permeability were improved. These dramatic improvements occurred with a small amount of added suberoyl chloride; excessive crosslinking led to membranes with unwanted poor permeability. Thus, both the mechanical properties and permeability of the crosslinked membrane can be optimized.
Keywords: chitosan; crosslink; N-phthaloylation; hydrophobicity; controlled release
PDF Full-text Download PDF Full-Text [1125 KB, uploaded 18 June 2014 20:07 CEST]

Export to BibTeX |
EndNote


MDPI and ACS Style

Chen, C.; Gao, Z.; Qiu, X.; Hu, S. Enhancement of the Controlled-Release Properties of Chitosan Membranes by Crosslinking with Suberoyl Chloride. Molecules 2013, 18, 7239-7252.

AMA Style

Chen C, Gao Z, Qiu X, Hu S. Enhancement of the Controlled-Release Properties of Chitosan Membranes by Crosslinking with Suberoyl Chloride. Molecules. 2013; 18(6):7239-7252.

Chicago/Turabian Style

Chen, Chao; Gao, Zideng; Qiu, Xiaoyun; Hu, Shuwen. 2013. "Enhancement of the Controlled-Release Properties of Chitosan Membranes by Crosslinking with Suberoyl Chloride." Molecules 18, no. 6: 7239-7252.

Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert