Next Article in Journal
Impact of Fruit Piece Structure in Yogurts on the Dynamics of Aroma Release and Sensory Perception
Previous Article in Journal
Different Analytical Approaches in Assessing Antibacterial Activity and the Purity of Commercial Lysozyme Preparations for Dairy Application
Molecules 2013, 18(5), 6021-6034; doi:10.3390/molecules18056021
Article

An Efficient Synthesis of Aldohexose-Derived Piperidine Nitrones: Precursors of Piperidine Iminosugars

, , ,  and *
Beijing National Laboratory for Molecular Science, CAS Key Laboratory of Molecular Recoganition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China
* Author to whom correspondence should be addressed.
Received: 7 May 2013 / Revised: 15 May 2013 / Accepted: 17 May 2013 / Published: 21 May 2013
(This article belongs to the Section Organic Synthesis)
Download PDF [251 KB, 18 June 2014; original version 18 June 2014]

Abstract

D-Glucopyranose-derived and L-idopyranose-derived piperidine nitrones were synthesized in good overall yields through six-step reaction sequence starting from readily available 2,3,4,6-tetra-O-benzyl-D-glucopyranose. The method is efficient and could be general for the synthesis of aldohexose-derived piperidine nitrones which are precursors of piperidine iminosugars.
Keywords: aldohexose-derived cyclic nitrones; synthesis; piperidine iminosugars aldohexose-derived cyclic nitrones; synthesis; piperidine iminosugars
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Share & Cite This Article

Export to BibTeX |
EndNote


MDPI and ACS Style

Zhao, H.; Zhao, W.-B.; Zhu, J.-S.; Jia, Y.-M.; Yu, C.-Y. An Efficient Synthesis of Aldohexose-Derived Piperidine Nitrones: Precursors of Piperidine Iminosugars. Molecules 2013, 18, 6021-6034.

View more citation formats

Supplement

Related Articles

Article Metrics

Comments

Citing Articles

[Return to top]
Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert