Molecules 2013, 18(5), 6021-6034; doi:10.3390/molecules18056021
Article

An Efficient Synthesis of Aldohexose-Derived Piperidine Nitrones: Precursors of Piperidine Iminosugars

Beijing National Laboratory for Molecular Science, CAS Key Laboratory of Molecular Recoganition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China
* Author to whom correspondence should be addressed.
Received: 7 May 2013; in revised form: 15 May 2013 / Accepted: 17 May 2013 / Published: 21 May 2013
(This article belongs to the Section Organic Synthesis)
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Abstract: D-Glucopyranose-derived and L-idopyranose-derived piperidine nitrones were synthesized in good overall yields through six-step reaction sequence starting from readily available 2,3,4,6-tetra-O-benzyl-D-glucopyranose. The method is efficient and could be general for the synthesis of aldohexose-derived piperidine nitrones which are precursors of piperidine iminosugars.
Keywords: aldohexose-derived cyclic nitrones; synthesis; piperidine iminosugars

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MDPI and ACS Style

Zhao, H.; Zhao, W.-B.; Zhu, J.-S.; Jia, Y.-M.; Yu, C.-Y. An Efficient Synthesis of Aldohexose-Derived Piperidine Nitrones: Precursors of Piperidine Iminosugars. Molecules 2013, 18, 6021-6034.

AMA Style

Zhao H, Zhao W-B, Zhu J-S, Jia Y-M, Yu C-Y. An Efficient Synthesis of Aldohexose-Derived Piperidine Nitrones: Precursors of Piperidine Iminosugars. Molecules. 2013; 18(5):6021-6034.

Chicago/Turabian Style

Zhao, Hui; Zhao, Wen-Bo; Zhu, Jian-She; Jia, Yue-Mei; Yu, Chu-Yi. 2013. "An Efficient Synthesis of Aldohexose-Derived Piperidine Nitrones: Precursors of Piperidine Iminosugars." Molecules 18, no. 5: 6021-6034.

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