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Molecules 2013, 18(5), 5723-5735; doi:10.3390/molecules18055723

Four New Citrinin Derivatives from a Marine-Derived Penicillium sp. Fungal Strain

School of Life Sciences, Xiamen University, 422 South Siming Road, Xiamen, Fujian 361005, China
Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Shandong University, Jinan, Shandong 250012, China
Author to whom correspondence should be addressed.
Received: 11 April 2013 / Revised: 9 May 2013 / Accepted: 10 May 2013 / Published: 16 May 2013
(This article belongs to the Section Natural Products)
View Full-Text   |   Download PDF [307 KB, uploaded 18 June 2014]   |  


Four new citrinin derivatives, including two citrinin dimers and two citrinin monomer derivatives, were isolated and identified from a marine-derived fungal strain Penicillium sp. ML226 along with six known related compounds. Their structures were elucidated by spectroscopic and chemical methods. The new compounds showed modest cytotoxic activity against HepG-2 cell line and weak antimicrobial activity against Staphylococcus aureus. View Full-Text
Keywords: citrinin; Penicillium sp. ML226; new metabolites; marine fungus citrinin; Penicillium sp. ML226; new metabolites; marine fungus

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MDPI and ACS Style

Wang, M.L.; Lu, C.H.; Xu, Q.Y.; Song, S.Y.; Hu, Z.Y.; Zheng, Z.H. Four New Citrinin Derivatives from a Marine-Derived Penicillium sp. Fungal Strain. Molecules 2013, 18, 5723-5735.

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