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Molecules 2013, 18(5), 5051-5058; doi:10.3390/molecules18055051
Article

Sesquiterpenoids from the Herb of Leonurus japonicus

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Received: 10 April 2013; in revised form: 24 April 2013 / Accepted: 25 April 2013 / Published: 29 April 2013
(This article belongs to the Section Metabolites)
Download PDF [238 KB, uploaded 18 June 2014]
Abstract: Two new sesquiterpenoids, (−)-(1S*,2S*,3R*)-3-ethoxycupar-5-ene-1,2-diol (1) and (−)-(1S*,4S*,9S*)-1,9-epoxybisabola-2,10-diene-4-ol (2), along with six known compounds 38, were isolated from the EtOH extract of the herb of Leonurus japonicus. Their structures were elucidated by physical and spectroscopic analysis. In the in vitro assays, compounds 7 and 8 showed obvious antibacterial activity against several bacteria strains, while compound 3 significantly inhibited abnormal increase of platelet aggregation induced by ADP.
Keywords: Leonurus japonicus; sesquiterpenoids; bioactivities Leonurus japonicus; sesquiterpenoids; bioactivities
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Xiong, L.; Zhou, Q.-M.; Peng, C.; Xie, X.-F.; Guo, L.; Li, X.-H.; Liu, J.; Liu, Z.-H.; Dai, O. Sesquiterpenoids from the Herb of Leonurus japonicus. Molecules 2013, 18, 5051-5058.

AMA Style

Xiong L, Zhou Q-M, Peng C, Xie X-F, Guo L, Li X-H, Liu J, Liu Z-H, Dai O. Sesquiterpenoids from the Herb of Leonurus japonicus. Molecules. 2013; 18(5):5051-5058.

Chicago/Turabian Style

Xiong, Liang; Zhou, Qin-Mei; Peng, Cheng; Xie, Xiao-Fang; Guo, Li; Li, Xiao-Hong; Liu, Juan; Liu, Zhao-Hua; Dai, Ou. 2013. "Sesquiterpenoids from the Herb of Leonurus japonicus." Molecules 18, no. 5: 5051-5058.


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