Molecules 2013, 18(4), 3917-3926; doi:10.3390/molecules18043917
Article

Bisucaberin B, a Linear Hydroxamate Class Siderophore from the Marine Bacterium Tenacibaculum mesophilum

1 Creative Research Institution, Hokkaido University, Hakodate 041-8611, Japan 2 Graduate School of Fisheries Sciences, Hokkaido University, Hakodate 041-8611, Japan
* Author to whom correspondence should be addressed.
Received: 16 February 2013; in revised form: 11 March 2013 / Accepted: 22 March 2013 / Published: 2 April 2013
(This article belongs to the Section Natural Products)
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Abstract: A siderophore, named bisucaberin B, was isolated from Tenacibaculum mesophilum bacteria separated from a marine sponge collected in the Republic of Palau. Using spectroscopic and chemical methods, the structure of bisucaberin B (1) was clearly determined to be a linear dimeric hydroxamate class siderophore. Although compound 1 is an open form of the known macrocyclic dimer bisucaberin (2), and was previously described as a bacterial degradation product of desferrioxamine B (4), the present report is the first description of the de novo biosynthesis of 1. To the best of our knowledge, compound 1 is the first chemically characterized siderophore isolated from a bacterium belonging to the phylum Bacteroidetes.
Keywords: siderophore; Tenacibaculum mesophilum; macrocycle; bisucaberin

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MDPI and ACS Style

Fujita, M.J.; Nakano, K.; Sakai, R. Bisucaberin B, a Linear Hydroxamate Class Siderophore from the Marine Bacterium Tenacibaculum mesophilum. Molecules 2013, 18, 3917-3926.

AMA Style

Fujita MJ, Nakano K, Sakai R. Bisucaberin B, a Linear Hydroxamate Class Siderophore from the Marine Bacterium Tenacibaculum mesophilum. Molecules. 2013; 18(4):3917-3926.

Chicago/Turabian Style

Fujita, Masaki J.; Nakano, Koji; Sakai, Ryuichi. 2013. "Bisucaberin B, a Linear Hydroxamate Class Siderophore from the Marine Bacterium Tenacibaculum mesophilum." Molecules 18, no. 4: 3917-3926.

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