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Molecules 2013, 18(4), 3641-3673; doi:10.3390/molecules18043641

A Survey of Marine Natural Compounds and Their Derivatives with Anti-Cancer Activity Reported in 2011

1,2, 1, 1, 1, 1 and 3,*
1 Laboratory of Molecular and Cellular Biology of Cancer (LBMCC), Hôpital Kirchberg, 9, rue Edward Steichen, L-2540 Luxembourg, Luxembourg 2 Institute of Health Sciences Research (IRSS), 03 BP 7192 Ouagadougou 03, Burkina Faso 3 Department of Pharmacy, College of Pharmacy, Seoul National University, Seoul 151-742, Korea
* Author to whom correspondence should be addressed.
Received: 14 February 2013 / Revised: 7 March 2013 / Accepted: 11 March 2013 / Published: 25 March 2013
(This article belongs to the Section Medicinal Chemistry)


Cancer continues to be a major public health problem despite the efforts that have been made in the search for novel drugs and treatments. The current sources sought for the discovery of new molecules are plants, animals and minerals. During the past decade, the search for anticancer agents of marine origin to fight chemo-resistance has increased greatly. Each year, several novel anticancer molecules are isolated from marine organisms and represent a renewed hope for cancer therapy. The study of structure-function relationships has allowed synthesis of analogues with increased efficacy and less toxicity. In this report, we aim to review 42 compounds of marine origin and their derivatives that were published in 2011 as promising anticancer compounds.
Keywords: anticancer molecules; marine origin; synthetic derivatives; cancer anticancer molecules; marine origin; synthetic derivatives; cancer
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Sawadogo, W.R.; Schumacher, M.; Teiten, M.-H.; Cerella, C.; Dicato, M.; Diederich, M. A Survey of Marine Natural Compounds and Their Derivatives with Anti-Cancer Activity Reported in 2011. Molecules 2013, 18, 3641-3673.

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