Volatiles, A Glutarimide Alkaloid and Antimicrobial Effects of Croton pullei (Euphorbiaceae)
AbstractChemical investigation of Croton pullei (Euphorbiaceae) collected in the Brazilian Amazon region was revisited. The chemical composition of the essential oils of leaves and stems was analyzed by GC/MS. It was found that both the oils comprise mainly terpenes, among which linalool was the major one (24.90 and 39.72%, respectively). Phytochemical investigation of the stem methanol extract led to the isolation of a new natural product from the glutarimide alkaloid group named N-[2,6-dioxo-1-(2-phenylethyl)-3-piperidinyl]-acetamide, confirming that C. pullei is a rich source of this class of alkaloids. The hexane and methanol extracts of the stems of C. pullei showed moderate antibacterial and antifungal activity and the highest inhibition was observed when the methanol extract was tested against Staphylococcus aureus CCMB 262 and CCMB 263. View Full-Text
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Peixoto, R.N.S.; Guilhon, G.M.S.P.; das Graças B. Zoghbi, M.; Araújo, I.S.; Uetanabaro, A.P.T.; Santos, L.S.; do S. B. Brasil, D. Volatiles, A Glutarimide Alkaloid and Antimicrobial Effects of Croton pullei (Euphorbiaceae). Molecules 2013, 18, 3195-3205.
Peixoto RNS, Guilhon GMSP, das Graças B. Zoghbi M, Araújo IS, Uetanabaro APT, Santos LS, do S. B. Brasil D. Volatiles, A Glutarimide Alkaloid and Antimicrobial Effects of Croton pullei (Euphorbiaceae). Molecules. 2013; 18(3):3195-3205.Chicago/Turabian Style
Peixoto, Rosana N.S.; Guilhon, Giselle M.S.P.; das Graças B. Zoghbi, Maria; Araújo, Isabella S.; Uetanabaro, Ana P.T.; Santos, Lourivaldo S.; do S. B. Brasil, Davi. 2013. "Volatiles, A Glutarimide Alkaloid and Antimicrobial Effects of Croton pullei (Euphorbiaceae)." Molecules 18, no. 3: 3195-3205.