Molecules 2013, 18(2), 1613-1625; doi:10.3390/molecules18021613
Article

Microwave-Assisted Improved Synthesis of Pyrrolo[2,3,4-kl]acridine and Dihydropyrrolo[2,3,4-kl]acridine Derivatives Catalyzed by Silica Sulfuric Acid

1,†, 2,†, 1, 3, 1, 2, 1, 1,* email and 2,* email
Received: 29 November 2012; in revised form: 21 December 2012 / Accepted: 5 January 2013 / Published: 28 January 2013
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: An improved synthesis of multifunctionalized pyrrolo[2,3,4-kl]acridine derivatives with different substituted patterns using silica sulfuric acid (SSA) as a heterogeneous catalyst under microwave irradiation conditions was developed. The reaction could be conducted by using readily available and inexpensive substrates within short periods of 12–15 min. under microwave irradiation. Compared with the conventional methods, the remarkable advantages of this method are milder reaction conditions, operational simplicity, higher yields, short reaction times, and an environmentally friendly procedure.
Keywords: pyrrolo[2,3,4-kl]acridine; silica sulfuric acid; microwave irradiation
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MDPI and ACS Style

Cao, C.; Xu, C.; Lin, W.; Li, X.; Hu, M.; Wang, J.; Huang, Z.; Shi, D.; Wang, Y. Microwave-Assisted Improved Synthesis of Pyrrolo[2,3,4-kl]acridine and Dihydropyrrolo[2,3,4-kl]acridine Derivatives Catalyzed by Silica Sulfuric Acid. Molecules 2013, 18, 1613-1625.

AMA Style

Cao C, Xu C, Lin W, Li X, Hu M, Wang J, Huang Z, Shi D, Wang Y. Microwave-Assisted Improved Synthesis of Pyrrolo[2,3,4-kl]acridine and Dihydropyrrolo[2,3,4-kl]acridine Derivatives Catalyzed by Silica Sulfuric Acid. Molecules. 2013; 18(2):1613-1625.

Chicago/Turabian Style

Cao, Chengpao; Xu, Changliang; Lin, Wei; Li, Xuemei; Hu, Minghua; Wang, Juxian; Huang, Zhibin; Shi, Daqing; Wang, Yucheng. 2013. "Microwave-Assisted Improved Synthesis of Pyrrolo[2,3,4-kl]acridine and Dihydropyrrolo[2,3,4-kl]acridine Derivatives Catalyzed by Silica Sulfuric Acid." Molecules 18, no. 2: 1613-1625.

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