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Molecules 2013, 18(12), 15717-15723; doi:10.3390/molecules181215717
Article

Synthesis of Dimethyl Aryl Acylsulfonium Bromides from Aryl Methyl Ketones in a DMSO-HBr System

1,* , 2, 2, 2, 2 and 3
1 Jiangsu Key Laboratory of Marine Biotechnology, Jiangsu Institute of Marine Resources, Huaihai Institute of Technology, Lianyungang 222005, China 2 School of Chemical Engineering, Huaihai Institute of Technology, Lianyungang 222005, China 3 School of Life Science, Beijing Institute of Technology, Beijing 100081, China
* Author to whom correspondence should be addressed.
Received: 26 November 2013 / Revised: 10 December 2013 / Accepted: 10 December 2013 / Published: 16 December 2013
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Abstract

A new, simplified method for the synthesis of dimethyl aryl acylsulfonium salts has been developed. A series of dimethyl aryl acylsulfonium bromides were prepared by the reaction of aryl methyl ketones with hydrobromic acid and dimethylsulfoxide (DMSO). This sulfonium salt confirms that bromine production and the bromination reaction take place in the DMSO-HBr oxidation system. What’s more, it is also a key intermediate for the synthesis of arylglyoxals.
Keywords: dimethyl aryl acylsulfonium; aryl methyl ketones; DMSO-HBr; synthesis; arylglyoxals dimethyl aryl acylsulfonium; aryl methyl ketones; DMSO-HBr; synthesis; arylglyoxals
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Cao, Z.; Shi, D.; Qu, Y.; Tao, C.; Liu, W.; Yao, G. Synthesis of Dimethyl Aryl Acylsulfonium Bromides from Aryl Methyl Ketones in a DMSO-HBr System. Molecules 2013, 18, 15717-15723.

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