Molecules 2013, 18(12), 15587-15599; doi:10.3390/molecules181215587
Article

Antimicrobial and Antioxidant Activities and Effect of 1-Hexadecene Addition on Palmarumycin C2 and C3 Yields in Liquid Culture of Endophytic Fungus Berkleasmium sp. Dzf12

1 MOA Key Laboratory of Plant Pathology, Department of Plant Pathology, College of Agronomy and Biotechnology, China Agricultural University, Beijing 100193, China 2 Department of Applied Chemistry, College of Science, China Agricultural University, Beijing 100193, China
* Author to whom correspondence should be addressed.
Received: 8 October 2013; in revised form: 3 December 2013 / Accepted: 9 December 2013 / Published: 13 December 2013
(This article belongs to the Section Natural Products)
PDF Full-text Download PDF Full-Text [289 KB, uploaded 13 December 2013 11:06 CET]
Abstract: Two spirobisnaphthalenes, namely palmarumycins C2 and C3, were isolated from cultures of the endophytic fungus Berkleasmium sp. Dzf12 after treatment with 1-hexadecene. After addition of 1-hexadecene at 10% to the medium on day 6 of culture, the maximal yields of palmarumycins C2 and C3 were obtained as 0.40 g/L and 1.19 g/L, which were 40.00 fold and 59.50 fold higher, respectively, in comparison with those of the control (0.01 g/L and 0.02 g/L). The results indicated that addition of 1-hexadecene can be an effective strategy for enhancing the production of palmarumycins C2 and C3 in liquid culture of endophytic fungus Berkleasmium sp. Dzf12. Palmarumycin C3 exhibited stronger antimicrobial and antioxidant activities than palmarumycin C2.
Keywords: spirobisnaphthalenes; palmarumycin C2; palmarumycin C3; endophytic fungus; Berkleasmium sp. Dzf12; 1-hexadecene; biological activity

Article Statistics

Load and display the download statistics.

Citations to this Article

Cite This Article

MDPI and ACS Style

Mou, Y.; Meng, J.; Fu, X.; Wang, X.; Tian, J.; Wang, M.; Peng, Y.; Zhou, L. Antimicrobial and Antioxidant Activities and Effect of 1-Hexadecene Addition on Palmarumycin C2 and C3 Yields in Liquid Culture of Endophytic Fungus Berkleasmium sp. Dzf12. Molecules 2013, 18, 15587-15599.

AMA Style

Mou Y, Meng J, Fu X, Wang X, Tian J, Wang M, Peng Y, Zhou L. Antimicrobial and Antioxidant Activities and Effect of 1-Hexadecene Addition on Palmarumycin C2 and C3 Yields in Liquid Culture of Endophytic Fungus Berkleasmium sp. Dzf12. Molecules. 2013; 18(12):15587-15599.

Chicago/Turabian Style

Mou, Yan; Meng, Jiajia; Fu, Xiaoxiang; Wang, Xiaohan; Tian, Jin; Wang, Mingan; Peng, Youliang; Zhou, Ligang. 2013. "Antimicrobial and Antioxidant Activities and Effect of 1-Hexadecene Addition on Palmarumycin C2 and C3 Yields in Liquid Culture of Endophytic Fungus Berkleasmium sp. Dzf12." Molecules 18, no. 12: 15587-15599.

Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert