Molecules 2013, 18(12), 15587-15599; doi:10.3390/molecules181215587
Article

Antimicrobial and Antioxidant Activities and Effect of 1-Hexadecene Addition on Palmarumycin C2 and C3 Yields in Liquid Culture of Endophytic Fungus Berkleasmium sp. Dzf12

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Received: 8 October 2013; in revised form: 3 December 2013 / Accepted: 9 December 2013 / Published: 13 December 2013
(This article belongs to the Section Metabolites)
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: Two spirobisnaphthalenes, namely palmarumycins C2 and C3, were isolated from cultures of the endophytic fungus Berkleasmium sp. Dzf12 after treatment with 1-hexadecene. After addition of 1-hexadecene at 10% to the medium on day 6 of culture, the maximal yields of palmarumycins C2 and C3 were obtained as 0.40 g/L and 1.19 g/L, which were 40.00 fold and 59.50 fold higher, respectively, in comparison with those of the control (0.01 g/L and 0.02 g/L). The results indicated that addition of 1-hexadecene can be an effective strategy for enhancing the production of palmarumycins C2 and C3 in liquid culture of endophytic fungus Berkleasmium sp. Dzf12. Palmarumycin C3 exhibited stronger antimicrobial and antioxidant activities than palmarumycin C2.
Keywords: spirobisnaphthalenes; palmarumycin C2; palmarumycin C3; endophytic fungus; Berkleasmium sp. Dzf12; 1-hexadecene; biological activity
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MDPI and ACS Style

Mou, Y.; Meng, J.; Fu, X.; Wang, X.; Tian, J.; Wang, M.; Peng, Y.; Zhou, L. Antimicrobial and Antioxidant Activities and Effect of 1-Hexadecene Addition on Palmarumycin C2 and C3 Yields in Liquid Culture of Endophytic Fungus Berkleasmium sp. Dzf12. Molecules 2013, 18, 15587-15599.

AMA Style

Mou Y, Meng J, Fu X, Wang X, Tian J, Wang M, Peng Y, Zhou L. Antimicrobial and Antioxidant Activities and Effect of 1-Hexadecene Addition on Palmarumycin C2 and C3 Yields in Liquid Culture of Endophytic Fungus Berkleasmium sp. Dzf12. Molecules. 2013; 18(12):15587-15599.

Chicago/Turabian Style

Mou, Yan; Meng, Jiajia; Fu, Xiaoxiang; Wang, Xiaohan; Tian, Jin; Wang, Mingan; Peng, Youliang; Zhou, Ligang. 2013. "Antimicrobial and Antioxidant Activities and Effect of 1-Hexadecene Addition on Palmarumycin C2 and C3 Yields in Liquid Culture of Endophytic Fungus Berkleasmium sp. Dzf12." Molecules 18, no. 12: 15587-15599.

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