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Molecules 2013, 18(1), 814-831; doi:10.3390/molecules18010814
Article

‘One-pot’ Synthesis of Dihydrobenzo[4,5][1,3]oxazino[2,3-a] isoquinolines via a Silver(I)-Catalyzed Cascade Approach

1, 2,* , 1, 1,2, 2 and 1,*
Received: 26 November 2012 / Revised: 4 January 2013 / Accepted: 5 January 2013 / Published: 11 January 2013
(This article belongs to the Section Organic Synthesis)
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Abstract

An efficient approach for the synthesis of biologically interesting fused tetracyclic isoquinolines in high yields and with a broad substrate scope has been developed. The strategy features an AgNO3 catalyzed ‘one-pot’ cascade process involving formation of two new C–N bonds and one new C–O bond.
Keywords: silver; one-pot; cascade transformation; isoquinolines; heterocyclic molecule silver; one-pot; cascade transformation; isoquinolines; heterocyclic molecule
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Jiang, B.; Zhou, Y.; Kong, Q.; Jiang, H.; Liu, H.; Li, J. ‘One-pot’ Synthesis of Dihydrobenzo[4,5][1,3]oxazino[2,3-a] isoquinolines via a Silver(I)-Catalyzed Cascade Approach. Molecules 2013, 18, 814-831.

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