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Molecules 2012, 17(9), 11281-11291; doi:10.3390/molecules170911281

In Vitro Antioxidant Properties of Flavonoids and Polysaccharides Extract from Tobacco (Nicotiana tabacum L.) Leaves

College of Biological and Environmental Engineering, Zhejiang University of Technology, Hangzhou 310032, China
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Received: 2 August 2012 / Revised: 11 September 2012 / Accepted: 12 September 2012 / Published: 21 September 2012
(This article belongs to the Section Natural Products)
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Abstract

In the present study, antioxidant properties of flavonoids and polysaccharides from tobacco (Nicotiana tabacum L.) leaves were evaluated in several in vitro systems, e.g., scavenging activities on hydroxyl, superoxide anion, 1,1-diphenyl-2-picrylhydrazyl (DPPH) and 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulphonic acid) (ABTS) radicals, and reducing power. Flavonoids showed much better activity than polysaccharides in scavenging activities on free radicals. When compared to the positive control, ascorbic acid, both showed weaker antioxidant potential. However, flavonoids possessed comparable superoxide anion, DPPH and ABTS radical scavenging abilities to ascorbic acid at high concentration (600 μg/mL). Meanwhile, it was found that flavonoids had prominent effects on the reducing power, which was equivalent to ascorbic acid, and was significantly higher than polysaccharides. These results clearly indicate that flavonoids are effective in scavenging free radicals and have the potential to be powerful antioxidants. Thus, tobacco leaves could be considered as a potential source of natural antioxidants for food, pharmaceutical, cosmetics or nutraceutical industries. View Full-Text
Keywords: tobacco (Nicotiana tabacum L.) leaves; flavonoids; polysaccharides; reducing power tobacco (Nicotiana tabacum L.) leaves; flavonoids; polysaccharides; reducing power
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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MDPI and ACS Style

Ru, Q.-M.; Wang, L.-J.; Li, W.-M.; Wang, J.-L.; Ding, Y.-T. In Vitro Antioxidant Properties of Flavonoids and Polysaccharides Extract from Tobacco (Nicotiana tabacum L.) Leaves. Molecules 2012, 17, 11281-11291.

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