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Bioactivities of the Genus Combretum (Combretaceae): A Review
Department of Pharmaceutical Sciences, Federal University of Paraiba, João Pessoa 58051-970, PB, Brazil
* Author to whom correspondence should be addressed.
Received: 18 May 2012; in revised form: 23 July 2012 / Accepted: 25 July 2012 / Published: 2 August 2012
Abstract: The Combretaceae is a large family of herbs, shrubs and trees, comprising about 20 genera and 600 species with tropical distribution around the globe and centers of diversity in Africa and Asia. Some Combretum species are extensively used in traditional medicine against inflammation, infections, diabetes, malaria, bleeding, diarrhea and digestive disorders and others as a diuretic. The present work is a literature survey of Combretum species that have been evaluated for their ability to exert biological activities. A total number of 36 Combretum species are discussed with regard to plant parts used, component tested and bioassay models. This review is of fundamental importance to promoting studies on Combretum species, thereby contributing to the development of new therapeutic alternatives that may improve the health of people suffering from various health problems.
Keywords: Combretaceae; Combretum; bioactivity; medicinal plants; natural products; review
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de Morais Lima, G.R.; de Sales, I.R.P.; Caldas Filho, M.R.D.; de Jesus, N.Z.T.; de Sousa Falcão, H.; Barbosa-Filho, J.M.; Cabral, A.G.S.; Souto, A.L.; Tavares, J.F.; Batista, L.M. Bioactivities of the Genus Combretum (Combretaceae): A Review. Molecules 2012, 17, 9142-9206.
de Morais Lima GR, de Sales IRP, Caldas Filho MRD, de Jesus NZT, de Sousa Falcão H, Barbosa-Filho JM, Cabral AGS, Souto AL, Tavares JF, Batista LM. Bioactivities of the Genus Combretum (Combretaceae): A Review. Molecules. 2012; 17(8):9142-9206.
de Morais Lima, Gedson Rodrigues; de Sales, Igor Rafael Praxedes; Caldas Filho, Marcelo Ricardo Dutra; de Jesus, Neyres Zínia Taveira; de Sousa Falcão, Heloina; Barbosa-Filho, José Maria; Cabral, Analúcia Guedes Silveira; Souto, Augusto Lopes; Tavares, Josean Fechine; Batista, Leônia Maria. 2012. "Bioactivities of the Genus Combretum (Combretaceae): A Review." Molecules 17, no. 8: 9142-9206.