Molecules 2012, 17(6), 6269-6276; doi:10.3390/molecules17066269
Article

α-Glucosidase Inhibitory Constituents from Acanthopanax senticosus Harm Leaves

Key Laboratory of Chinese Materia Medica (Ministry of Education), Heilongjiang University of Chinese Medicine, Harbin 150040, China
* Author to whom correspondence should be addressed.
Received: 19 April 2012; in revised form: 16 May 2012 / Accepted: 21 May 2012 / Published: 25 May 2012
PDF Full-text Download PDF Full-Text [249 KB, uploaded 25 May 2012 14:51 CEST]
Abstract: A new triterpene glycoside, 3-O-[(α-L-rhamnopyranosyl)(1→2)]-[β-D-glucuronopyranosyl-6-O-methyl ester]-olean-12-ene-28-olic acid (1) and a new indole alkaloid, 5-methoxy-2-oxoindolin-3-acetic acid methyl ester (5) were isolated from the leaves of Acanthopanax senticosus Harms along with six known compounds. The structures of the new compounds were determined by means of 2D-NMR experiments and chemical methods. All the isolated compounds were evaluated for their glycosidase inhibition activities and compound 6 showed significant α-glucosidase inhibition activity.
Keywords: Acanthopanax senticosus Harms; triterpene glycoside; alkaloid; α-glucosidase inhibition activity

Article Statistics

Load and display the download statistics.

Citations to this Article

Cite This Article

MDPI and ACS Style

Wang, Z.-B.; Jiang, H.; Xia, Y.-G.; Yang, B.-Y.; Kuang, H.-X. α-Glucosidase Inhibitory Constituents from Acanthopanax senticosus Harm Leaves. Molecules 2012, 17, 6269-6276.

AMA Style

Wang Z-B, Jiang H, Xia Y-G, Yang B-Y, Kuang H-X. α-Glucosidase Inhibitory Constituents from Acanthopanax senticosus Harm Leaves. Molecules. 2012; 17(6):6269-6276.

Chicago/Turabian Style

Wang, Zhi-Bin; Jiang, Hai; Xia, Yong-Gang; Yang, Bing-You; Kuang, Hai-Xue. 2012. "α-Glucosidase Inhibitory Constituents from Acanthopanax senticosus Harm Leaves." Molecules 17, no. 6: 6269-6276.

Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert