Molecules 2012, 17(5), 5544-5549; doi:10.3390/molecules17055544
Article

Two New Aryltetralin Lignans from the Roots of Dolomiaea souliei

Hua Wei 1,2 , Chunnian He 1,2 , Yong Peng 1,2 , Sen Zhang 3 , Xiaoguang Chen 3  and Peigen Xiao 1,2,* email
1 Institute of Medicinal Plant Development, Chinese Academy of Medical Science & Peking Union Medical College, Beijing 100193, China 2 Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Peking Union Medical College, Beijing 100193, China 3 Institute of Materia Medica, Chinese Academy of Medical Science & Peking Union Medical College, Beijing 100193, China
* Author to whom correspondence should be addressed.
Received: 9 April 2012; in revised form: 26 April 2012 / Accepted: 27 April 2012 / Published: 9 May 2012
(This article belongs to the Section Natural Products)
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Abstract: Two new aryltetralin-type lignans, dolomiaeasin A (1) and dolomiaeasin B (2), were isolated from the roots of Dolomiaea souliei. Their structures were elucidated by means of various spectroscopic analyses. The cytotoxicities of 1 and 2 were tested by the MTT method, and both compounds showed no significant cytotoxic activities against the A549 and A2780 human cancer cell lines. This is the first time that aryltetralin-type lignans were isolated from the genus Dolomiaea.
Keywords: Compositae; Dolomiaea souliei; aryltetralin; cytotoxicity

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MDPI and ACS Style

Wei, H.; He, C.; Peng, Y.; Zhang, S.; Chen, X.; Xiao, P. Two New Aryltetralin Lignans from the Roots of Dolomiaea souliei. Molecules 2012, 17, 5544-5549.

AMA Style

Wei H, He C, Peng Y, Zhang S, Chen X, Xiao P. Two New Aryltetralin Lignans from the Roots of Dolomiaea souliei. Molecules. 2012; 17(5):5544-5549.

Chicago/Turabian Style

Wei, Hua; He, Chunnian; Peng, Yong; Zhang, Sen; Chen, Xiaoguang; Xiao, Peigen. 2012. "Two New Aryltetralin Lignans from the Roots of Dolomiaea souliei." Molecules 17, no. 5: 5544-5549.

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