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Molecules 2012, 17(3), 3501-3509; doi:10.3390/molecules17033501

Synthesis and Structural Determination of Novel 5-Arylidene-3-N(2-alkyloxyaryl)-2-thioxothiazolidin-4-ones

Laboratoire de Synthèse Organique Appliquée, BP 1524, El Menaouer, Université d’Oran Es-Senia, 31000 Oran, Algérie
Laboratoire de Structure, Elaboration et Applications des Matériaux Moléculaires (SEA2M), Département de Génie des Procédés, Faculté des Sciences et de la Technologie, Université de Mostaganem, 27000 Mostaganem, Algérie
Author to whom correspondence should be addressed.
Received: 5 January 2012 / Revised: 26 February 2012 / Accepted: 1 March 2012 / Published: 19 March 2012
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As part of our project devoted to the synthesis of heterocycles including thiazole rings, some new 5-arylidene-2-thioxo-3-N-arylthiazolidin-4-ones were synthesized by Knoevenagel condensation. An interesting feature of these compounds is that their chirality is induced by that of their 3-N-(2-alkyloxyaryl)-2-thioxothiazolidin-4-one precursors, which in turn is due to the presence of a C2 axis of chirality. These new compounds were characterized by spectroscopic methods (IR, 1H-NMR, 13C-NMR). The structure of compound (Z)-(2g) was further determined by X-ray diffraction.
Keywords: N-arylthiazolidin-4-one; (Z)-5-arylidene-3-N-arylthiazolidin-4-one; chirality; IR; 1H-NMR; 13C-NMR; X-ray diffraction; nonlinear optical properties; solar cells N-arylthiazolidin-4-one; (Z)-5-arylidene-3-N-arylthiazolidin-4-one; chirality; IR; 1H-NMR; 13C-NMR; X-ray diffraction; nonlinear optical properties; solar cells

This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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Toubal, K.; Djafri, A.; Chouaih, A.; Talbi, A. Synthesis and Structural Determination of Novel 5-Arylidene-3-N(2-alkyloxyaryl)-2-thioxothiazolidin-4-ones. Molecules 2012, 17, 3501-3509.

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