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Update of Spectroscopic Data for 4-Hydroxydictyolactone and Dictyol E Isolated from a Halimeda stuposa — Dictyota sp. Assemblage†
Australian Institute of Marine Science, PMB no. 3, Townsville MC, Townsville, 4810, Australia
Present address: Defence Science & Technology Organisation, 506 Lorimer St. Fishermans Bend, Victoria, 3207, Australia; E-Mail: email@example.com
Present address: ACD Labs UK, Building A, Trinity Court, Wokingham Road, Bracknell, Berkshire, RG42 1PL, UK; E-Mail: firstname.lastname@example.org
Present address: James Cook University, Townsville, Queensland 4811, Australia; E-Mail: email@example.com
Present address: University of Hawaii, College of Pharmacy, 34 Rainbow Drive, Hilo, HI 96720, USA; E-Mail: firstname.lastname@example.org
† Dedication: We dedicate this paper to the late Peter Thomas Murphy (Townsville, Australia) for his passionate contributions to Australian natural products chemistry and marine biodiversity research.
* Author to whom correspondence should be addressed.
Received: 7 February 2012; in revised form: 23 February 2012 / Accepted: 5 March 2012 / Published: 8 March 2012
Abstract: The methanol extract of an assemblage of Halimeda stuposa and a Dictyota sp., yielded three natural products characteristic of Dictyota sp., and one of Halimeda sp. These included the xenicane diterpene 4-hydroxydictyolactone (1), and the diterpenes dictyol E (2), 8a,11-dihydroxypachydictyol A (3) and indole-3-carboxaldehyde (4). A minor revision of 1 and new spectroscopic data for 1 and 2 are provided, along with associated anti-cancer activities of compounds 1–4.
Keywords: Dictyota; Dictyotaceae; Halimeda stuposa; anti-cancer activity; xenicanes; diterpenes; 4-hydroxydictyolactone; dictyol E; 8a,11-dihydroxypachydictyol A; indole-3-carboxaldehyde
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Ovenden, S.P.B.; Nielson, J.L.; Liptrot, C.H.; Willis, R.H.; Tapiolas, D.M.; Wright, A.D.; Motti, C.A. Update of Spectroscopic Data for 4-Hydroxydictyolactone and Dictyol E Isolated from a Halimeda stuposa — Dictyota sp. Assemblage. Molecules 2012, 17, 2929-2938.
Ovenden SPB, Nielson JL, Liptrot CH, Willis RH, Tapiolas DM, Wright AD, Motti CA. Update of Spectroscopic Data for 4-Hydroxydictyolactone and Dictyol E Isolated from a Halimeda stuposa — Dictyota sp. Assemblage. Molecules. 2012; 17(3):2929-2938.
Ovenden, Simon P. B.; Nielson, Jonathan L.; Liptrot, Catherine H.; Willis, Richard H.; Tapiolas, Dianne M.; Wright, Anthony D.; Motti, Cherie A. 2012. "Update of Spectroscopic Data for 4-Hydroxydictyolactone and Dictyol E Isolated from a Halimeda stuposa — Dictyota sp. Assemblage." Molecules 17, no. 3: 2929-2938.