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Key to Xenobiotic Carotenoids
Molecules 2012, 17(3), 2929-2938; doi:10.3390/molecules17032929
Article

Update of Spectroscopic Data for 4-Hydroxydictyolactone and Dictyol E Isolated from a Halimeda stuposaDictyota sp. Assemblage

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Australian Institute of Marine Science, PMB no. 3, Townsville MC, Townsville, 4810, Australia Present address: Defence Science & Technology Organisation, 506 Lorimer St. Fishermans Bend, Victoria, 3207, Australia; E-Mail: simon.ovenden@dsto.defence.gov.au § Present address: ACD Labs UK, Building A, Trinity Court, Wokingham Road, Bracknell, Berkshire, RG42 1PL, UK; E-Mail: jonathon.nielson@acdlabs.com || Present address: James Cook University, Townsville, Queensland 4811, Australia; E-Mail: catherine.liptrot@jcu.edu.au Present address: University of Hawaii, College of Pharmacy, 34 Rainbow Drive, Hilo, HI 96720, USA; E-Mail: adwright@hawaii.edu
Dedication: We dedicate this paper to the late Peter Thomas Murphy (Townsville, Australia) for his passionate contributions to Australian natural products chemistry and marine biodiversity research.
* Author to whom correspondence should be addressed.
Received: 7 February 2012 / Revised: 23 February 2012 / Accepted: 5 March 2012 / Published: 8 March 2012
(This article belongs to the Section Metabolites)
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Abstract

The methanol extract of an assemblage of Halimeda stuposa and a Dictyota sp., yielded three natural products characteristic of Dictyota sp., and one of Halimeda sp. These included the xenicane diterpene 4-hydroxydictyolactone (1), and the diterpenes dictyol E (2), 8a,11-dihydroxypachydictyol A (3) and indole-3-carboxaldehyde (4). A minor revision of 1 and new spectroscopic data for 1 and 2 are provided, along with associated anti-cancer activities of compounds 14.
Keywords: Dictyota; Dictyotaceae; Halimeda stuposa; anti-cancer activity; xenicanes; diterpenes; 4-hydroxydictyolactone; dictyol E; 8a,11-dihydroxypachydictyol A; indole-3-carboxaldehyde Dictyota; Dictyotaceae; Halimeda stuposa; anti-cancer activity; xenicanes; diterpenes; 4-hydroxydictyolactone; dictyol E; 8a,11-dihydroxypachydictyol A; indole-3-carboxaldehyde
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Ovenden, S.P.B.; Nielson, J.L.; Liptrot, C.H.; Willis, R.H.; Tapiolas, D.M.; Wright, A.D.; Motti, C.A. Update of Spectroscopic Data for 4-Hydroxydictyolactone and Dictyol E Isolated from a Halimeda stuposaDictyota sp. Assemblage. Molecules 2012, 17, 2929-2938.

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