Molecules 2012, 17(2), 1992-1999; doi:10.3390/molecules17021992
Article

Allylic Alkylations Catalyzed By Palladium-Bis(oxazoline) Complexes Derived From Heteroarylidene Malonate Derivatives

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Received: 14 November 2011; in revised form: 19 January 2012 / Accepted: 6 February 2012 / Published: 17 February 2012
(This article belongs to the Section Theoretical Chemistry)
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: A series of simple heteroarylidene malonate-type bis(oxazoline) ligands 4 and 5 were applied to the Palladium-catalyzed allylic alkylation reaction, and the ligand 4a bearing a phenyl group afforded excellent enantioselectivity (up to 96% ee) for the allylic alkylation product. Other substrates were also examined, giving the allylic alkylated products in high yield but with poor ee values.
Keywords: bis(oxazoline); asymmetric catalysis; allylic alkylation
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MDPI and ACS Style

Liu, L.; Ma, H.; Fu, B. Allylic Alkylations Catalyzed By Palladium-Bis(oxazoline) Complexes Derived From Heteroarylidene Malonate Derivatives. Molecules 2012, 17, 1992-1999.

AMA Style

Liu L, Ma H, Fu B. Allylic Alkylations Catalyzed By Palladium-Bis(oxazoline) Complexes Derived From Heteroarylidene Malonate Derivatives. Molecules. 2012; 17(2):1992-1999.

Chicago/Turabian Style

Liu, Lei; Ma, Hongli; Fu, Bin. 2012. "Allylic Alkylations Catalyzed By Palladium-Bis(oxazoline) Complexes Derived From Heteroarylidene Malonate Derivatives." Molecules 17, no. 2: 1992-1999.

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