Next Article in Journal
Impact of Halogen Substituents on Interactions between 2-Phenyl-2,3-dihydroqulinazolin-4(1H)-one Derivatives and Human Serum Albumin
Previous Article in Journal
Enhancement of Mechanical and Thermal Properties of Oil Palm Empty Fruit Bunch Fiber Poly(butylene adipate-co-terephtalate) Biocomposites by Matrix Esterification Using Succinic Anhydride
Article Menu

Article Versions

Export Article

Open AccessArticle
Molecules 2012, 17(2), 1992-1999; doi:10.3390/molecules17021992

Allylic Alkylations Catalyzed By Palladium-Bis(oxazoline) Complexes Derived From Heteroarylidene Malonate Derivatives

Department of Applied Chemistry, China Agricultural University, Beijing 100193, China
Author to whom correspondence should be addressed.
Received: 14 November 2011 / Revised: 19 January 2012 / Accepted: 6 February 2012 / Published: 17 February 2012
(This article belongs to the Section Organic Synthesis)
Download PDF [206 KB, uploaded 18 June 2014]   |  


A series of simple heteroarylidene malonate-type bis(oxazoline) ligands 4 and 5 were applied to the Palladium-catalyzed allylic alkylation reaction, and the ligand 4a bearing a phenyl group afforded excellent enantioselectivity (up to 96% ee) for the allylic alkylation product. Other substrates were also examined, giving the allylic alkylated products in high yield but with poor ee values.
Keywords: bis(oxazoline); asymmetric catalysis; allylic alkylation bis(oxazoline); asymmetric catalysis; allylic alkylation

This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Supplementary material

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Liu, L.; Ma, H.; Fu, B. Allylic Alkylations Catalyzed By Palladium-Bis(oxazoline) Complexes Derived From Heteroarylidene Malonate Derivatives. Molecules 2012, 17, 1992-1999.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics



[Return to top]

Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top