Next Article in Journal
Impact of Halogen Substituents on Interactions between 2-Phenyl-2,3-dihydroqulinazolin-4(1H)-one Derivatives and Human Serum Albumin
Previous Article in Journal
Enhancement of Mechanical and Thermal Properties of Oil Palm Empty Fruit Bunch Fiber Poly(butylene adipate-co-terephtalate) Biocomposites by Matrix Esterification Using Succinic Anhydride
Molecules 2012, 17(2), 1992-1999; doi:10.3390/molecules17021992
Article

Allylic Alkylations Catalyzed By Palladium-Bis(oxazoline) Complexes Derived From Heteroarylidene Malonate Derivatives

,
 and *
Received: 14 November 2011; in revised form: 19 January 2012 / Accepted: 6 February 2012 / Published: 17 February 2012
(This article belongs to the Section Organic Synthesis)
Download PDF [206 KB, uploaded 18 June 2014]
Abstract: A series of simple heteroarylidene malonate-type bis(oxazoline) ligands 4 and 5 were applied to the Palladium-catalyzed allylic alkylation reaction, and the ligand 4a bearing a phenyl group afforded excellent enantioselectivity (up to 96% ee) for the allylic alkylation product. Other substrates were also examined, giving the allylic alkylated products in high yield but with poor ee values.
Keywords: bis(oxazoline); asymmetric catalysis; allylic alkylation bis(oxazoline); asymmetric catalysis; allylic alkylation
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Export to BibTeX |
EndNote


MDPI and ACS Style

Liu, L.; Ma, H.; Fu, B. Allylic Alkylations Catalyzed By Palladium-Bis(oxazoline) Complexes Derived From Heteroarylidene Malonate Derivatives. Molecules 2012, 17, 1992-1999.

AMA Style

Liu L, Ma H, Fu B. Allylic Alkylations Catalyzed By Palladium-Bis(oxazoline) Complexes Derived From Heteroarylidene Malonate Derivatives. Molecules. 2012; 17(2):1992-1999.

Chicago/Turabian Style

Liu, Lei; Ma, Hongli; Fu, Bin. 2012. "Allylic Alkylations Catalyzed By Palladium-Bis(oxazoline) Complexes Derived From Heteroarylidene Malonate Derivatives." Molecules 17, no. 2: 1992-1999.


Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert