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Molecules 2012, 17(10), 12061-12071; doi:10.3390/molecules171012061
Article

Synthesis and Photophysical Study of 2′-Deoxyuridines Labeled with Fluorene Derivatives

1
, 2,*  and 1,*
1 Department of Chemistry and Green-Nano Materials Research Center, Kyungpook National University, Daegu 702-701, Korea 2 Molecular Imaging Research Center, Korea Institute of Radiological and Medical Sciences, 75 Nowon-gil, Seoul 139-706, Korea
* Authors to whom correspondence should be addressed.
Received: 14 September 2012 / Revised: 3 October 2012 / Accepted: 10 October 2012 / Published: 15 October 2012
(This article belongs to the Special Issue Nucleic Acid Analogs)
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Abstract

We examined microenvironment-sensitive fluorescent 2′-deoxyuridines labeled with fluorene derivatives that exhibited solvent-dependent photophysical properties. The high sensitivity of the fluorescence shift and the nucleoside intensity dependence on solvent polarity provided information useful for estimating the polarity of the environment surrounding the fluorescent nucleoside.
Keywords: nucleosides; fluorene; fluorescence; dibenzofuran; dibenzothiophene nucleosides; fluorene; fluorescence; dibenzofuran; dibenzothiophene
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Cho, H.Y.; Woo, S.K.; Hwang, G.T. Synthesis and Photophysical Study of 2′-Deoxyuridines Labeled with Fluorene Derivatives. Molecules 2012, 17, 12061-12071.

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