Next Article in Journal
Antiviral Properties of Lactoferrin—A Natural Immunity Molecule
Previous Article in Journal
Antimicrobial and Antioxidant Activities of New Metal Complexes Derived from 3-Aminocoumarin
Article Menu

Article Versions

Export Article

Open AccessArticle
Molecules 2011, 16(8), 6985-6991; doi:10.3390/molecules16086985

Synthesis of New Riminophenazines with Pyrimidine and Pyrazine Substitution at the 2-N Position

Department of Medicinal Chemistry, Beijing Key Laboratory of Active Substance Discovery and Drugability Evaluation, Institute of Materia Medica, Peking Union Medical College and Chinese Academy of Medical Sciences, 1 Xian Nong Tan Street, Beijing 100050, China
Author to whom correspondence should be addressed.
Received: 11 July 2011 / Revised: 6 August 2011 / Accepted: 9 August 2011 / Published: 16 August 2011
Download PDF [477 KB, uploaded 18 June 2014]


New riminophenazines with pyrimidine and pyrazine substituents at the 2-position were successfully synthesized. The key step is the 2-N-arylation of riminophenazines with pyrimidine and pyrazine. The optimized reaction conditions involve the use of a Pd2(dba)3/DPPF/Cs2CO3/toluene combination.
Keywords: riminophenazine; N-arylation; palladium catalyst riminophenazine; N-arylation; palladium catalyst
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Zhang, G.; Zhang, H.; Wang, X.; Li, C.; Huang, H.; Yin, D. Synthesis of New Riminophenazines with Pyrimidine and Pyrazine Substitution at the 2-N Position. Molecules 2011, 16, 6985-6991.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics



[Return to top]
Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top