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Molecules 2011, 16(8), 6985-6991; doi:10.3390/molecules16086985
Article

Synthesis of New Riminophenazines with Pyrimidine and Pyrazine Substitution at the 2-N Position

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Received: 11 July 2011 / Revised: 6 August 2011 / Accepted: 9 August 2011 / Published: 16 August 2011
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Abstract

New riminophenazines with pyrimidine and pyrazine substituents at the 2-position were successfully synthesized. The key step is the 2-N-arylation of riminophenazines with pyrimidine and pyrazine. The optimized reaction conditions involve the use of a Pd2(dba)3/DPPF/Cs2CO3/toluene combination.
Keywords: riminophenazine; N-arylation; palladium catalyst riminophenazine; N-arylation; palladium catalyst
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Zhang, G.; Zhang, H.; Wang, X.; Li, C.; Huang, H.; Yin, D. Synthesis of New Riminophenazines with Pyrimidine and Pyrazine Substitution at the 2-N Position. Molecules 2011, 16, 6985-6991.

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