Next Article in Journal
Synthesis and Cytotoxic Activity of Some New 2,6-Substituted Purines
Previous Article in Journal
Characterization and Determination of the Alkaloid Metabolites of Evodiae fructus in Rat Urine by Liquid Chromatography-Tandem Mass Spectrometry Detection
Molecules 2011, 16(7), 5833-5839; doi:10.3390/molecules16075833

Two New Withanolide Lactones from Flos Daturae

* , ,  and
Key Laboratory of Chinese Materia Medica, Heilongjiang University of Chinese Medicine, Ministry of Education, Harbin 150040, China
* Author to whom correspondence should be addressed.
Received: 1 June 2011 / Revised: 29 June 2011 / Accepted: 5 July 2011 / Published: 11 July 2011
Download PDF [172 KB, uploaded 18 June 2014]


Chemical investigation of the 50% ethanol eluate fraction from a macroporous resin of flowers of Datura metel L. collected in the Jiangsu Province of China resulted in the isolation of two new withanolides, baimantuoluoline G (1) and baimantuoluoside H (2). Their structures were elucidated as (12β,6β,22R)-1,10-seco-6,12,27-trihydroxy-26-oxo-witha-3,5,24-trienolide-1-oic acid-ε-lactone (1) and (5β,6α,12β,22R)-5,6,12,27-tetra-hydroxy-1,26-dioxo-witha-2,24-dienolide-27-O-β-glucopyranoside (2) on the basis of extensive spectroscopic analysis (1D, 2D-NMR and HRESIMS) and chemical studies.
Keywords: Flos Daturae; Datura metel L.; withanolide lactones Flos Daturae; Datura metel L.; withanolide lactones
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Share & Cite This Article

Further Mendeley | CiteULike
Export to BibTeX |
EndNote |
MDPI and ACS Style

Kuang, H.-X.; Yang, B.-Y.; Xia, Y.-G.; Wang, Q.-H. Two New Withanolide Lactones from Flos Daturae. Molecules 2011, 16, 5833-5839.

View more citation formats

Related Articles

Article Metrics

For more information on the journal, click here


[Return to top]
Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert