Next Article in Journal
Synthesis and Cytotoxic Activity of Some New 2,6-Substituted Purines
Previous Article in Journal
Characterization and Determination of the Alkaloid Metabolites of Evodiae fructus in Rat Urine by Liquid Chromatography-Tandem Mass Spectrometry Detection
Article Menu

Article Versions

Export Article

Open AccessArticle
Molecules 2011, 16(7), 5833-5839; doi:10.3390/molecules16075833

Two New Withanolide Lactones from Flos Daturae

Key Laboratory of Chinese Materia Medica, Heilongjiang University of Chinese Medicine, Ministry of Education, Harbin 150040, China
Author to whom correspondence should be addressed.
Received: 1 June 2011 / Revised: 29 June 2011 / Accepted: 5 July 2011 / Published: 11 July 2011
Download PDF [172 KB, uploaded 18 June 2014]


Chemical investigation of the 50% ethanol eluate fraction from a macroporous resin of flowers of Datura metel L. collected in the Jiangsu Province of China resulted in the isolation of two new withanolides, baimantuoluoline G (1) and baimantuoluoside H (2). Their structures were elucidated as (12β,6β,22R)-1,10-seco-6,12,27-trihydroxy-26-oxo-witha-3,5,24-trienolide-1-oic acid-ε-lactone (1) and (5β,6α,12β,22R)-5,6,12,27-tetra-hydroxy-1,26-dioxo-witha-2,24-dienolide-27-O-β-glucopyranoside (2) on the basis of extensive spectroscopic analysis (1D, 2D-NMR and HRESIMS) and chemical studies.
Keywords: Flos Daturae; Datura metel L.; withanolide lactones Flos Daturae; Datura metel L.; withanolide lactones
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Kuang, H.-X.; Yang, B.-Y.; Xia, Y.-G.; Wang, Q.-H. Two New Withanolide Lactones from Flos Daturae. Molecules 2011, 16, 5833-5839.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics



[Return to top]

Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top