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Molecules 2011, 16(7), 5833-5839; doi:10.3390/molecules16075833

Two New Withanolide Lactones from Flos Daturae

* , ,  and
Key Laboratory of Chinese Materia Medica, Heilongjiang University of Chinese Medicine, Ministry of Education, Harbin 150040, China
* Author to whom correspondence should be addressed.
Received: 1 June 2011 / Revised: 29 June 2011 / Accepted: 5 July 2011 / Published: 11 July 2011
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Chemical investigation of the 50% ethanol eluate fraction from a macroporous resin of flowers of Datura metel L. collected in the Jiangsu Province of China resulted in the isolation of two new withanolides, baimantuoluoline G (1) and baimantuoluoside H (2). Their structures were elucidated as (12β,6β,22R)-1,10-seco-6,12,27-trihydroxy-26-oxo-witha-3,5,24-trienolide-1-oic acid-ε-lactone (1) and (5β,6α,12β,22R)-5,6,12,27-tetra-hydroxy-1,26-dioxo-witha-2,24-dienolide-27-O-β-glucopyranoside (2) on the basis of extensive spectroscopic analysis (1D, 2D-NMR and HRESIMS) and chemical studies.
Keywords: Flos Daturae; Datura metel L.; withanolide lactones Flos Daturae; Datura metel L.; withanolide lactones
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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Kuang, H.-X.; Yang, B.-Y.; Xia, Y.-G.; Wang, Q.-H. Two New Withanolide Lactones from Flos Daturae. Molecules 2011, 16, 5833-5839.

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