Next Article in Journal
A Survey of Marine Natural Compounds and Their Derivatives with Anti-Cancer Activity Reported in 2010
Previous Article in Journal
Unsymmetrical Mesoporphyrinic Complexes of Copper (II) and Zinc (II). Microwave-Assisted Synthesis, Spectral Characterization and Cytotoxicity Evaluation
Molecules 2011, 16(7), 5618-5628; doi:10.3390/molecules16075618

Synthesis and Antifungal Activities of Some Novel Pyrimidine Derivatives

, , ,  and *
Marine College, Shandong University, Weihai Wenhua West Road, No.180, Weihai 264209, China
* Author to whom correspondence should be addressed.
Received: 24 May 2011 / Revised: 16 June 2011 / Accepted: 17 June 2011 / Published: 30 June 2011
Download PDF [223 KB, uploaded 18 June 2014]


Three series of new pyrimidine derivatives were synthesized and their antifungal activities were evaluated in vitro against fourteen phytopathogenic fungi. The results indicated that most of the synthesized compounds possessed fungicidal activities and some of them are more potent than the control fungicides. Preliminary SAR was also discussed.
Keywords: pyrimidine derivatives; synthesis; antifungal activity; SAR pyrimidine derivatives; synthesis; antifungal activity; SAR
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Share & Cite This Article

Further Mendeley | CiteULike
Export to BibTeX |
MDPI and ACS Style

Sun, L.; Wu, J.; Zhang, L.; Luo, M.; Sun, D. Synthesis and Antifungal Activities of Some Novel Pyrimidine Derivatives. Molecules 2011, 16, 5618-5628.

View more citation formats

Related Articles

Article Metrics

For more information on the journal, click here


Cited By

[Return to top]
Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert