Synthesis and Antifungal Activities of Some Novel Pyrimidine Derivatives

doi:10.3390/molecules16075618

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Molecules 2011, 16(7), 5618-5628; doi:10.3390/molecules16075618

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Synthesis and Antifungal Activities of Some Novel Pyrimidine Derivatives

Li Sun, Jie Wu, Lingzi Zhang, Min Luo and Dequn Sun*

Marine College, Shandong University, Weihai Wenhua West Road, No.180, Weihai 264209, China

* Author to whom correspondence should be addressed.

Received: 24 May 2011; in revised form: 16 June 2011 / Accepted: 17 June 2011 / Published: 30 June 2011

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Abstract: Three series of new pyrimidine derivatives were synthesized and their antifungal activities were evaluated in vitro against fourteen phytopathogenic fungi. The results indicated that most of the synthesized compounds possessed fungicidal activities and some of them are more potent than the control fungicides. Preliminary SAR was also discussed.

Keywords: pyrimidine derivatives; synthesis; antifungal activity; SAR

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Cite This Article

MDPI and ACS Style

Sun, L.; Wu, J.; Zhang, L.; Luo, M.; Sun, D. Synthesis and Antifungal Activities of Some Novel Pyrimidine Derivatives. Molecules 2011, 16, 5618-5628.

AMA Style

Sun L, Wu J, Zhang L, Luo M, Sun D. Synthesis and Antifungal Activities of Some Novel Pyrimidine Derivatives. Molecules. 2011; 16(7):5618-5628.

Chicago/Turabian Style

Sun, Li; Wu, Jie; Zhang, Lingzi; Luo, Min; Sun, Dequn. 2011. "Synthesis and Antifungal Activities of Some Novel Pyrimidine Derivatives." Molecules 16, no. 7: 5618-5628.

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