Next Article in Journal
Two New Iridoid Glycosides from the Root Barks of Sambucus williamsii Hance
Next Article in Special Issue
Synthesis, Properties Characterization and Applications of Various Organobismuth Compounds
Previous Article in Journal
Optimization of the Selective Monohydrolysis of Diethyl 4-Aryl-4H-pyran-3,5-dicarboxylates
Previous Article in Special Issue
Irving-Williams Order in the Framework of Connectivity Index 3χv Enables Simultaneous Prediction of Stability Constants of Bivalent Transition Metal Complexes
Molecules 2011, 16(5), 3855-3868; doi:10.3390/molecules16053855

RuCl3·3H2O Catalyzed Reactions: Facile Synthesis of Bis(indolyl)methanes under Mild Conditions

*  and *
Department of Chemistry and Biology, Gannan Normal University, Ganzhou, Jiangxi 341000, China
* Authors to whom correspondence should be addressed.
Received: 23 March 2011 / Revised: 20 April 2011 / Accepted: 25 April 2011 / Published: 9 May 2011
(This article belongs to the Special Issue Organometallic Chemistry)
Download PDF [225 KB, uploaded 18 June 2014]


RuCl3·3H2O was found to be an effective catalyst for reactions of indoles, 2-methylthiophene, and 2-methylfuran with aldehydes to afford the corresponding bis(indolyl)methanes, bis(thienyl)methanes, and bis(fur-2-yl)methanes in moderate to excellent yields. Experimental results indicated that mono(indolyl)methanol is not the reaction intermediate under these reaction conditions.
Keywords: bis(indolyl)methane; RuCl3·3H2O; aldehyde; indole bis(indolyl)methane; RuCl3·3H2O; aldehyde; indole
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Share & Cite This Article

Further Mendeley | CiteULike
Export to BibTeX |
EndNote |
MDPI and ACS Style

Qu, H.-E.; Xiao, C.; Wang, N.; Yu, K.-H.; Hu, Q.-S.; Liu, L.-X. RuCl3·3H2O Catalyzed Reactions: Facile Synthesis of Bis(indolyl)methanes under Mild Conditions. Molecules 2011, 16, 3855-3868.

View more citation formats

Related Articles

Article Metrics

For more information on the journal, click here


[Return to top]
Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert