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Molecules 2011, 16(5), 3855-3868; doi:10.3390/molecules16053855
Article

RuCl3·3H2O Catalyzed Reactions: Facile Synthesis of Bis(indolyl)methanes under Mild Conditions

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Received: 23 March 2011; in revised form: 20 April 2011 / Accepted: 25 April 2011 / Published: 9 May 2011
(This article belongs to the Special Issue Organometallic Chemistry)
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Abstract: RuCl3·3H2O was found to be an effective catalyst for reactions of indoles, 2-methylthiophene, and 2-methylfuran with aldehydes to afford the corresponding bis(indolyl)methanes, bis(thienyl)methanes, and bis(fur-2-yl)methanes in moderate to excellent yields. Experimental results indicated that mono(indolyl)methanol is not the reaction intermediate under these reaction conditions.
Keywords: bis(indolyl)methane; RuCl3·3H2O; aldehyde; indole bis(indolyl)methane; RuCl3·3H2O; aldehyde; indole
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Qu, H.-E.; Xiao, C.; Wang, N.; Yu, K.-H.; Hu, Q.-S.; Liu, L.-X. RuCl3·3H2O Catalyzed Reactions: Facile Synthesis of Bis(indolyl)methanes under Mild Conditions. Molecules 2011, 16, 3855-3868.

AMA Style

Qu H-E, Xiao C, Wang N, Yu K-H, Hu Q-S, Liu L-X. RuCl3·3H2O Catalyzed Reactions: Facile Synthesis of Bis(indolyl)methanes under Mild Conditions. Molecules. 2011; 16(5):3855-3868.

Chicago/Turabian Style

Qu, Hong-En; Xiao, Chen; Wang, Ning; Yu, Kai-Hui; Hu, Qiao-Sheng; Liu, Liang-Xian. 2011. "RuCl3·3H2O Catalyzed Reactions: Facile Synthesis of Bis(indolyl)methanes under Mild Conditions." Molecules 16, no. 5: 3855-3868.


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