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Molecules 2011, 16(3), 2268-2273; doi:10.3390/molecules16032268

Lignans and Other Constituents from Aerial Parts of Haplophyllum Villosum

, * , ,  and
Department of Chemistry, Faculty of Science, Universiti Putra Malaysia, 43400 Serdang, Selangor, Malaysia
* Author to whom correspondence should be addressed.
Received: 14 January 2011 / Revised: 28 January 2011 / Accepted: 17 February 2011 / Published: 7 March 2011
(This article belongs to the collection Bioactive Compounds)
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During our phytochemical investigation of Haplophyllum villosum (Rutaceae), a perennial herb from Iran, a new 4,8-diaryl-3,7-dioxobicyclo-(3,3,0)-octane type lignan, eudesmin A (1), together with four known compounds–eudesmin (2), haplamine (3), umbelliferone (4) and scopoletin (5)–were isolated from aerial parts of the plant. The structures of the compounds were elucidated using NMR spectral analysis (1H-NMR, 13C-NMR, HSQC, COSY and HMBC) as well as UV, IR and MS spectra and comparison with previously reported data.
Keywords: Haplophyllum villosum; Rutaceae; eudesmin A; Eudesmin; haplamine Haplophyllum villosum; Rutaceae; eudesmin A; Eudesmin; haplamine
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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Parhoodeh, P.; Rahmani, M.; Hashim, N.M.; Sukari, M.A.; Cheng Lian, G.E. Lignans and Other Constituents from Aerial Parts of Haplophyllum Villosum. Molecules 2011, 16, 2268-2273.

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