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Molecules 2011, 16(2), 1901-1909; doi:10.3390/molecules16021901
Article

Three New Steroidal Glycosides from the Roots of Cynanchum auriculatum

1, 2, 1 and 1,*
1 Laboratory for Natural Product Chemistry, College of Pharmacy, South Central University for Nationalities, Wuhan 430074, China 2 Guangxi Institute of Minority Medicine, Nanning 530001, China
* Author to whom correspondence should be addressed.
Received: 15 November 2010 / Revised: 16 February 2011 / Accepted: 18 February 2011 / Published: 23 February 2011
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Abstract

Three new steroidal glycosides, cyanoauriculosides F, G and H (1-3), were isolated from the roots of Cynanchum auriculatum (Asclepiadaceae) along with two known steroidal derivatives. On the basis of spectroscopic analysis and chemical methods, their structures were identified as 20-O-acetyl-8,14-seco-penupogenin-8-one 3-O-α-L-cymaropyranosyl-(1→4)-β-D-cymaropyranosyl-(1→4)-α-L-diginopyranosyl-(1→4)-β-D-cymaropyranoside (1), 2′,3′-Z-gagaminine 3-O-α-L-cymaropyranosyl-(1→4)-β-D-cymaro-pyranosyl-(1→4)-α-L-diginopyranosyl-(1→4)-β-D-cymaropyranoside (2), 17-O-acetyl-kidjoranin 3-O-α-L-cymaropyranosyl-(1→4)-β-D-cymaropyranosyl-(1→4)-α-L-cymaro-pyranosyl-(1→4)-β-D-digitoxopyranosyl-(1→4)-β-D-digitoxopyranoside (3), gagaminine 3-O-α-L-cymaropyranosyl-(1→4)-β-D-cymaropyranosyl-(1→4)-α-L-digino-pyranosyl-(1→4)-β-D-cymaropyranoside (4) and wilfoside D1N (5).
Keywords: Cynanchum auriculatum; steroidal glycosides; cyanoauriculosides Cynanchum auriculatum; steroidal glycosides; cyanoauriculosides
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Lu, Y.; Teng, H.-L.; Yang, G.-Z.; Mei, Z.-N. Three New Steroidal Glycosides from the Roots of Cynanchum auriculatum. Molecules 2011, 16, 1901-1909.

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