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Molecules 2011, 16(2), 1901-1909; doi:10.3390/molecules16021901

Three New Steroidal Glycosides from the Roots of Cynanchum auriculatum

1, 2, 1 and 1,*
1 Laboratory for Natural Product Chemistry, College of Pharmacy, South Central University for Nationalities, Wuhan 430074, China 2 Guangxi Institute of Minority Medicine, Nanning 530001, China
* Author to whom correspondence should be addressed.
Received: 15 November 2010 / Revised: 16 February 2011 / Accepted: 18 February 2011 / Published: 23 February 2011
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Three new steroidal glycosides, cyanoauriculosides F, G and H (1-3), were isolated from the roots of Cynanchum auriculatum (Asclepiadaceae) along with two known steroidal derivatives. On the basis of spectroscopic analysis and chemical methods, their structures were identified as 20-O-acetyl-8,14-seco-penupogenin-8-one 3-O-α-L-cymaropyranosyl-(1→4)-β-D-cymaropyranosyl-(1→4)-α-L-diginopyranosyl-(1→4)-β-D-cymaropyranoside (1), 2′,3′-Z-gagaminine 3-O-α-L-cymaropyranosyl-(1→4)-β-D-cymaro-pyranosyl-(1→4)-α-L-diginopyranosyl-(1→4)-β-D-cymaropyranoside (2), 17-O-acetyl-kidjoranin 3-O-α-L-cymaropyranosyl-(1→4)-β-D-cymaropyranosyl-(1→4)-α-L-cymaro-pyranosyl-(1→4)-β-D-digitoxopyranosyl-(1→4)-β-D-digitoxopyranoside (3), gagaminine 3-O-α-L-cymaropyranosyl-(1→4)-β-D-cymaropyranosyl-(1→4)-α-L-digino-pyranosyl-(1→4)-β-D-cymaropyranoside (4) and wilfoside D1N (5).
Keywords: Cynanchum auriculatum; steroidal glycosides; cyanoauriculosides Cynanchum auriculatum; steroidal glycosides; cyanoauriculosides
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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Lu, Y.; Teng, H.-L.; Yang, G.-Z.; Mei, Z.-N. Three New Steroidal Glycosides from the Roots of Cynanchum auriculatum. Molecules 2011, 16, 1901-1909.

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