Molecules 2011, 16(2), 1642-1654; doi:10.3390/molecules16021642
Article

Peppermint Oil Decreases the Production of Virulence-Associated Exoproteins by Staphylococcus aureus

Jing Li † email, Jing Dong † email, Jia-Zhang Qiu † email, Jian-Feng Wangemail, Ming-Jing Luoemail, Hong-En Liemail, Bing-Feng Lengemail, Wen-Zhi Ren* email and Xu-Ming Deng* email
Key Laboratory of Zoonosis, Ministry of Education, Institute of Zoonosis, College of Animal Science and Veterinary Medicine, Jilin University, Changchun 130062, China † These authors contributed equally to this work.
* Authors to whom correspondence should be addressed.
Received: 30 November 2010; in revised form: 8 February 2011 / Accepted: 10 February 2011 / Published: 15 February 2011
PDF Full-text Download PDF Full-Text [471 KB, uploaded 15 February 2011 11:42 CET]
Abstract: The present study aimed to evaluate the antimicrobial activity of peppermint oil against Staphylococcus aureus, and further investigate the influence of peppermint oil on S. aureus virulence-related exoprotein production. The data show that peppermint oil, which contained high contents of menthone, isomenthone, neomenthol, menthol, and menthyl acetate, was active against S. aureus with minimal inhibitory concentrations (MICs) ranging from 64-256 µg/mL, and the production of S. aureus exotoxins was decreased by subinhibitory concentrations of peppermint oil in a dose-dependent manner. The findings suggest that peppermint oil may potentially be used to aid in the treatment of S. aureus infections.
Keywords: Staphylococcus aureus; peppermint oil; α-toxin; staphylococcal enterotoxins; toxic shock syndrome toxin 1

Article Statistics

Click here to load and display the download statistics.

Cite This Article

MDPI and ACS Style

Li, J.; Dong, J.; Qiu, J.-Z.; Wang, J.-F.; Luo, M.-J.; Li, H.-E.; Leng, B.-F.; Ren, W.-Z.; Deng, X.-M. Peppermint Oil Decreases the Production of Virulence-Associated Exoproteins by Staphylococcus aureus. Molecules 2011, 16, 1642-1654.

AMA Style

Li J, Dong J, Qiu J-Z, Wang J-F, Luo M-J, Li H-E, Leng B-F, Ren W-Z, Deng X-M. Peppermint Oil Decreases the Production of Virulence-Associated Exoproteins by Staphylococcus aureus. Molecules. 2011; 16(2):1642-1654.

Chicago/Turabian Style

Li, Jing; Dong, Jing; Qiu, Jia-Zhang; Wang, Jian-Feng; Luo, Ming-Jing; Li, Hong-En; Leng, Bing-Feng; Ren, Wen-Zhi; Deng, Xu-Ming. 2011. "Peppermint Oil Decreases the Production of Virulence-Associated Exoproteins by Staphylococcus aureus." Molecules 16, no. 2: 1642-1654.

Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert