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Molecules 2011, 16(2), 1642-1654; doi:10.3390/molecules16021642
Article

Peppermint Oil Decreases the Production of Virulence-Associated Exoproteins by Staphylococcus aureus

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Received: 30 November 2010; in revised form: 8 February 2011 / Accepted: 10 February 2011 / Published: 15 February 2011
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Abstract: The present study aimed to evaluate the antimicrobial activity of peppermint oil against Staphylococcus aureus, and further investigate the influence of peppermint oil on S. aureus virulence-related exoprotein production. The data show that peppermint oil, which contained high contents of menthone, isomenthone, neomenthol, menthol, and menthyl acetate, was active against S. aureus with minimal inhibitory concentrations (MICs) ranging from 64-256 µg/mL, and the production of S. aureus exotoxins was decreased by subinhibitory concentrations of peppermint oil in a dose-dependent manner. The findings suggest that peppermint oil may potentially be used to aid in the treatment of S. aureus infections.
Keywords: Staphylococcus aureus; peppermint oil; α-toxin; staphylococcal enterotoxins; toxic shock syndrome toxin 1 Staphylococcus aureus; peppermint oil; α-toxin; staphylococcal enterotoxins; toxic shock syndrome toxin 1
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Li, J.; Dong, J.; Qiu, J.-Z.; Wang, J.-F.; Luo, M.-J.; Li, H.-E.; Leng, B.-F.; Ren, W.-Z.; Deng, X.-M. Peppermint Oil Decreases the Production of Virulence-Associated Exoproteins by Staphylococcus aureus. Molecules 2011, 16, 1642-1654.

AMA Style

Li J, Dong J, Qiu J-Z, Wang J-F, Luo M-J, Li H-E, Leng B-F, Ren W-Z, Deng X-M. Peppermint Oil Decreases the Production of Virulence-Associated Exoproteins by Staphylococcus aureus. Molecules. 2011; 16(2):1642-1654.

Chicago/Turabian Style

Li, Jing; Dong, Jing; Qiu, Jia-Zhang; Wang, Jian-Feng; Luo, Ming-Jing; Li, Hong-En; Leng, Bing-Feng; Ren, Wen-Zhi; Deng, Xu-Ming. 2011. "Peppermint Oil Decreases the Production of Virulence-Associated Exoproteins by Staphylococcus aureus." Molecules 16, no. 2: 1642-1654.



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