Molecules 2011, 16(2), 1192-1200; doi:10.3390/molecules16021192
Article

Crystal Structure and Hydrogen Bonding Study of (10E)-2,2-Dimethyl-3,4-dihydro-2H-benzo[g]chromene-5,10-dione 10-Oxime Derived From a-Lapachone

Andrea R. Da Silva 1 , Marcelo H. Herbst 1,* email, Aurelio B. B. Ferreira 1 , Ari M. Da Silva 1  and Lorenzo C. Visentin 2,* email
1 Departamento de Química, Universidade Federal Rural do Rio de Janeiro, BR 465, km 47, Seropédica, RJ, 23890-000, Brazil 2 Instituto de Química, Universidade Federal do Rio de Janeiro, Avenida Athos da Silveira Ramos, 149, Bloco A, 7° andar, Cidade Universitária, Rio de Janeiro, RJ, 21941-909, Brazil
* Authors to whom correspondence should be addressed.
Received: 15 October 2010; in revised form: 25 January 2011 / Accepted: 26 January 2011 / Published: 27 January 2011
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Abstract: The compound (10E)-2,2-dimethyl-3,4-dihydro-2H-benzo[g]chromene-5,10-dione-10-oxime (1) was synthesized from a-lapachone and hydroxylamine chloride in alkaline medium. Single-crystals suitable for X-ray diffraction measurements were grown from an ethanol solution, and the crystal structure of the title molecule is reported for the first time. The title molecule was also characterized by 1H- and 13C-NMR in CDCl3 solution, FTIR and MS. The crystal structure of 1 shows an E stereochemistry and dimers formed through classical hydrogen bonds.
Keywords: oxime; crystal structure; hydrogen bond  

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MDPI and ACS Style

Da Silva, A.R.; Herbst, M.H.; Ferreira, A.B.B.; Da Silva, A.M.; Visentin, L.C. Crystal Structure and Hydrogen Bonding Study of (10E)-2,2-Dimethyl-3,4-dihydro-2H-benzo[g]chromene-5,10-dione 10-Oxime Derived From a-Lapachone. Molecules 2011, 16, 1192-1200.

AMA Style

Da Silva AR, Herbst MH, Ferreira ABB, Da Silva AM, Visentin LC. Crystal Structure and Hydrogen Bonding Study of (10E)-2,2-Dimethyl-3,4-dihydro-2H-benzo[g]chromene-5,10-dione 10-Oxime Derived From a-Lapachone. Molecules. 2011; 16(2):1192-1200.

Chicago/Turabian Style

Da Silva, Andrea R.; Herbst, Marcelo H.; Ferreira, Aurelio B. B.; Da Silva, Ari M.; Visentin, Lorenzo C. 2011. "Crystal Structure and Hydrogen Bonding Study of (10E)-2,2-Dimethyl-3,4-dihydro-2H-benzo[g]chromene-5,10-dione 10-Oxime Derived From a-Lapachone." Molecules 16, no. 2: 1192-1200.

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