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Molecules 2011, 16(12), 9972-9982; doi:10.3390/molecules16129972
Article

Isolation of C11 Compounds and a Cyclopropane Fatty Acid from an Okinawan Ascidian, Diplosoma sp.

1, 1,2
,
1, 3
 and
1,*
1 Department of Chemistry, Biology and Marine Science, University of the Ryukyus, Nishihara-cho Okinawa 903-0123, Japan 2 Okinawa Industrial Technology Center, Uruma-shi Okinawa 904-2234, Japan 3 Department of Bioresources Engineering, Okinawa National College of Technology, Nago-shi Okinawa 905-2192, Japan
* Author to whom correspondence should be addressed.
Received: 7 November 2011 / Revised: 29 November 2011 / Accepted: 30 November 2011 / Published: 2 December 2011
(This article belongs to the Section Natural Products)
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Abstract

Pentylphenols 1 and 2, cyclopropane fatty acid 3, and cyclopentenones 4 and 5, were isolated from an ascidian, Diplosoma sp. The structures of 1-5 were determined by spectroscopic analysis and/or synthesis. Compound 1 inhibited the division of fertilized sea urchin eggs and compound 4 showed mild cytotoxity against HCT116 cells (human colorectal cancer cell).
Keywords: ascidian; Diplosoma sp.; cytotoxity; NMR ascidian; Diplosoma sp.; cytotoxity; NMR
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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Rob, T.; Ogi, T.; Maarisit, W.; Taira, J.; Ueda, K. Isolation of C11 Compounds and a Cyclopropane Fatty Acid from an Okinawan Ascidian, Diplosoma sp.. Molecules 2011, 16, 9972-9982.

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