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Molecules 2011, 16(12), 9972-9982; doi:10.3390/molecules16129972
Article

Isolation of C11 Compounds and a Cyclopropane Fatty Acid from an Okinawan Ascidian, Diplosoma sp.

1, 1,2
,
1, 3
 and
1,*
Received: 7 November 2011 / Revised: 29 November 2011 / Accepted: 30 November 2011 / Published: 2 December 2011
(This article belongs to the Section Metabolites)
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Abstract

Pentylphenols 1 and 2, cyclopropane fatty acid 3, and cyclopentenones 4 and 5, were isolated from an ascidian, Diplosoma sp. The structures of 1-5 were determined by spectroscopic analysis and/or synthesis. Compound 1 inhibited the division of fertilized sea urchin eggs and compound 4 showed mild cytotoxity against HCT116 cells (human colorectal cancer cell).
Keywords: ascidian; Diplosoma sp.; cytotoxity; NMR ascidian; Diplosoma sp.; cytotoxity; NMR
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Rob, T.; Ogi, T.; Maarisit, W.; Taira, J.; Ueda, K. Isolation of C11 Compounds and a Cyclopropane Fatty Acid from an Okinawan Ascidian, Diplosoma sp.. Molecules 2011, 16, 9972-9982.

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