Next Article in Journal
Inhibitors of Testosterone Biosynthetic and Metabolic Activation Enzymes
Previous Article in Journal
Structural and Molecular Characterization of meso-Substituted Zinc Porphyrins: A DFT Supported Study
Molecules 2011, 16(12), 9972-9982; doi:10.3390/molecules16129972

Isolation of C11 Compounds and a Cyclopropane Fatty Acid from an Okinawan Ascidian, Diplosoma sp.

1, 1,2
1, 3
1 Department of Chemistry, Biology and Marine Science, University of the Ryukyus, Nishihara-cho Okinawa 903-0123, Japan 2 Okinawa Industrial Technology Center, Uruma-shi Okinawa 904-2234, Japan 3 Department of Bioresources Engineering, Okinawa National College of Technology, Nago-shi Okinawa 905-2192, Japan
* Author to whom correspondence should be addressed.
Received: 7 November 2011 / Revised: 29 November 2011 / Accepted: 30 November 2011 / Published: 2 December 2011
(This article belongs to the Section Metabolites)
Download PDF [271 KB, uploaded 18 June 2014]


Pentylphenols 1 and 2, cyclopropane fatty acid 3, and cyclopentenones 4 and 5, were isolated from an ascidian, Diplosoma sp. The structures of 1-5 were determined by spectroscopic analysis and/or synthesis. Compound 1 inhibited the division of fertilized sea urchin eggs and compound 4 showed mild cytotoxity against HCT116 cells (human colorectal cancer cell).
Keywords: ascidian; Diplosoma sp.; cytotoxity; NMR ascidian; Diplosoma sp.; cytotoxity; NMR
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Share & Cite This Article

Further Mendeley | CiteULike
Export to BibTeX |
MDPI and ACS Style

Rob, T.; Ogi, T.; Maarisit, W.; Taira, J.; Ueda, K. Isolation of C11 Compounds and a Cyclopropane Fatty Acid from an Okinawan Ascidian, Diplosoma sp.. Molecules 2011, 16, 9972-9982.

View more citation formats

Related Articles

Article Metrics

For more information on the journal, click here


Cited By

[Return to top]
Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert