Molecules 2011, 16(11), 9553-9561; doi:10.3390/molecules16119553

One-Pot Synthesis of Novel 2,3-Dihydro-1H-indazoles

* email and
Received: 8 October 2011; in revised form: 8 November 2011 / Accepted: 10 November 2011 / Published: 16 November 2011
(This article belongs to the Special Issue Heterocycles)
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: A copper(I)-mediated one-pot synthesis of 2,3-dihydro-1H-indazole heterocycles has been developed. This synthetic route provides the desired indazoles in moderate to good yields (55%–72%) which are substantially better than those achievable with an alternative two-step reaction sequence. The reaction is tolerant of functionality on the aromatic ring.
Keywords: 2,3-dihydro-1H-indazole; synthesis; heterocycle; indazoles; copper coupling
PDF Full-text Download PDF Full-Text [237 KB, uploaded 18 June 2014 19:41 CEST]

Export to BibTeX |

MDPI and ACS Style

Breton, G.W.; Lepore, A.J. One-Pot Synthesis of Novel 2,3-Dihydro-1H-indazoles. Molecules 2011, 16, 9553-9561.

AMA Style

Breton GW, Lepore AJ. One-Pot Synthesis of Novel 2,3-Dihydro-1H-indazoles. Molecules. 2011; 16(11):9553-9561.

Chicago/Turabian Style

Breton, Gary W.; Lepore, Antonio J. 2011. "One-Pot Synthesis of Novel 2,3-Dihydro-1H-indazoles." Molecules 16, no. 11: 9553-9561.

Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert