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Molecules 2011, 16(11), 9553-9561; doi:10.3390/molecules16119553
Article

One-Pot Synthesis of Novel 2,3-Dihydro-1H-indazoles

*  and
Department of Chemistry, Berry College, PO Box 495016, Mount Berry, GA 30101, USA
* Author to whom correspondence should be addressed.
Received: 8 October 2011 / Revised: 8 November 2011 / Accepted: 10 November 2011 / Published: 16 November 2011
(This article belongs to the Special Issue Heterocycles)
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Abstract

A copper(I)-mediated one-pot synthesis of 2,3-dihydro-1H-indazole heterocycles has been developed. This synthetic route provides the desired indazoles in moderate to good yields (55%–72%) which are substantially better than those achievable with an alternative two-step reaction sequence. The reaction is tolerant of functionality on the aromatic ring.
Keywords: 2,3-dihydro-1H-indazole; synthesis; heterocycle; indazoles; copper coupling 2,3-dihydro-1H-indazole; synthesis; heterocycle; indazoles; copper coupling
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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Breton, G.W.; Lepore, A.J. One-Pot Synthesis of Novel 2,3-Dihydro-1H-indazoles. Molecules 2011, 16, 9553-9561.

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