Xanthate Based Radical Cascade Toward Multicomponent Formation of Pyrrolopyrimidines

doi:10.3390/molecules16119261

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Molecules 2011, 16(11), 9261-9273; doi:10.3390/molecules16119261

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Xanthate Based Radical Cascade Toward Multicomponent Formation of Pyrrolopyrimidines

Laurent El Kaïm* , Laurence Grimaud* and Patil Pravin

Laboratoire DCSO ENSTA-Polytechnique-CNRS, UMR 7652, Ecole Nationale Supérieure de Techniques Avancées, 32 Bd Victor, 75739 Paris Cedex 15, France

* Authors to whom correspondence should be addressed.

Received: 28 September 2011; in revised form: 23 October 2011 / Accepted: 28 October 2011 / Published: 4 November 2011

(This article belongs to the Special Issue Multicomponent Reaction)

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Abstract: A short sequential synthesis of pyrrolidino- pyridines and pyrimidines illustrates the potential of combining Ugi-Smiles couplings with radical tin-free processes.

Keywords: Ugi-Smiles coupling; xanthates; multicomponent reactions; radical processes; isocyanides

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MDPI and ACS Style

Kaïm, L.E.; Grimaud, L.; Pravin, P. Xanthate Based Radical Cascade Toward Multicomponent Formation of Pyrrolopyrimidines. Molecules 2011, 16, 9261-9273.

AMA Style

Kaïm LE, Grimaud L, Pravin P. Xanthate Based Radical Cascade Toward Multicomponent Formation of Pyrrolopyrimidines. Molecules. 2011; 16(11):9261-9273.

Chicago/Turabian Style

Kaïm, Laurent El; Grimaud, Laurence; Pravin, Patil. 2011. "Xanthate Based Radical Cascade Toward Multicomponent Formation of Pyrrolopyrimidines." Molecules 16, no. 11: 9261-9273.

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