Molecules 2011, 16(10), 8733-8744; doi:10.3390/molecules16108733
Article

Efficient Microwave-Assisted Synthesis of Ionic Esterified Amino Acids

Received: 16 September 2011; in revised form: 11 October 2011 / Accepted: 14 October 2011 / Published: 19 October 2011
(This article belongs to the Special Issue Microwave Assisted Synthesis)
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: In this work, an efficient microwave-assisted methodology for the esterification of unprotected α-amino acids is described. Ionic esterified amino acids were synthesized in satisfactory yields in a facile one-pot solventless protocol from unprotected amino acids and alcohols under acid catalysis (MsOH or p-TsOH) to afford the pure products after a simple work-up procedure. This procedure can also be extended to the preparation of long and short chain alkyl and benzyl esters.
Keywords: amino acids; esterification; microwave; parallel synthesis
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MDPI and ACS Style

Cerón-Camacho, R.; Aburto, J.; Montiel, L.E.; Flores, E.A.; Cuellar, F.; Martínez-Palou, R. Efficient Microwave-Assisted Synthesis of Ionic Esterified Amino Acids. Molecules 2011, 16, 8733-8744.

AMA Style

Cerón-Camacho R, Aburto J, Montiel LE, Flores EA, Cuellar F, Martínez-Palou R. Efficient Microwave-Assisted Synthesis of Ionic Esterified Amino Acids. Molecules. 2011; 16(10):8733-8744.

Chicago/Turabian Style

Cerón-Camacho, Ricardo; Aburto, Jorge; Montiel, Luisa E.; Flores, Eugenio A.; Cuellar, Frisia; Martínez-Palou, Rafael. 2011. "Efficient Microwave-Assisted Synthesis of Ionic Esterified Amino Acids." Molecules 16, no. 10: 8733-8744.

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