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Molecules 2011, 16(10), 8143-8151; doi:10.3390/molecules16108143

DNA-Templated Preparation of Gold Nanoparticles

1,* , 2
1 Department of Chemical and Biochemical Engineering, Chosun University, Gwangju, 501-759, South Korea 2 Department of Chemistry, Korea University, Seoul, 136-701, South Korea
* Authors to whom correspondence should be addressed.
Received: 6 September 2011 / Revised: 19 September 2011 / Accepted: 20 September 2011 / Published: 27 September 2011
(This article belongs to the Special Issue DNA-Templated Synthesis)
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DNA-mediated gold nanoparticles were prepared by chemical reduction of DNA-Au(III) complex. The DNA-Au(III) was first formed by reacting DNA with HAuCl4 at a pH of 5.6. The complex in solution was reacted with hydrazine reducing Au(III) to Au. The reduced Au formed nanodimensional aggregates. The particle distributions were obtained by scanning electron microscopy (SEM) and transmission electron microscopy (TEM). This method resulted in a rather uniform dispersion of Au nanoparticles of near-spherical shape and 45~80 nm in diameter. Gold nanoparticles were embedded and stabilized by DNA.
Keywords: DNA-Au complexes; DNA-mediated; gold nanoparticles DNA-Au complexes; DNA-mediated; gold nanoparticles
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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Sohn, J.S.; Kwon, Y.W.; Jin, J.I.; Jo, B.W. DNA-Templated Preparation of Gold Nanoparticles. Molecules 2011, 16, 8143-8151.

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