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DNA-Templated Preparation of Gold Nanoparticles
Department of Chemical and Biochemical Engineering, Chosun University, Gwangju, 501-759, South Korea
Department of Chemistry, Korea University, Seoul, 136-701, South Korea
* Authors to whom correspondence should be addressed.
Received: 6 September 2011; in revised form: 19 September 2011 / Accepted: 20 September 2011 / Published: 27 September 2011
Abstract: DNA-mediated gold nanoparticles were prepared by chemical reduction of DNA-Au(III) complex. The DNA-Au(III) was first formed by reacting DNA with HAuCl4 at a pH of 5.6. The complex in solution was reacted with hydrazine reducing Au(III) to Au. The reduced Au formed nanodimensional aggregates. The particle distributions were obtained by scanning electron microscopy (SEM) and transmission electron microscopy (TEM). This method resulted in a rather uniform dispersion of Au nanoparticles of near-spherical shape and 45~80 nm in diameter. Gold nanoparticles were embedded and stabilized by DNA.
Keywords: DNA-Au complexes; DNA-mediated; gold nanoparticles
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MDPI and ACS Style
Sohn, J.S.; Kwon, Y.W.; Jin, J.I.; Jo, B.W. DNA-Templated Preparation of Gold Nanoparticles. Molecules 2011, 16, 8143-8151.
Sohn JS, Kwon YW, Jin JI, Jo BW. DNA-Templated Preparation of Gold Nanoparticles. Molecules. 2011; 16(10):8143-8151.
Sohn, Jeong Sun; Kwon, Young Wan; Jin, Jung Il; Jo, Byung Wook. 2011. "DNA-Templated Preparation of Gold Nanoparticles." Molecules 16, no. 10: 8143-8151.